Negative Correlation Found Between Alpha, Beta Carotene and Parkinson's Disease

ea179698-38e5-420c-b63f-93ff932ca69barticleimage.jpg

25 May 2017 --- A new study has shown that serum alpha-carotene, beta-carotene and lycopene may contribute to increased risk and progression of Parkinson’s disease (PD). According to the authors, the study's findings support the notion that carotenes play an important role in the pathogenesis and progression of PD. Serum levels of antioxidants such as alpha-carotene, beta-carotene, retinol, alpha- and gamma-tocopherol, lutein, zeaxanthin and beta-cryptoxanthin were measured and compared between 104 patients with idiopathic PD (Early PD: Hoehn and Yahr stage I and II, N = 47; and Advanced PD: Hoehn and Yahr stage III and IV, N = 57) and 52 healthy controls matched for age and gender. 

The correlation analyses of serum antioxidants and PD progression were performed using Hoehn and Yahr stage and Unified Parkinson’s Disease Rating Scale (UPDRS) motor score to indicate early PD and advanced PD, respectively.

When compared to control, all PD patients showed lower levels of alpha-carotene, beta-carotene and lycopene and negative correlation between Hoehn and Yahr stage and UPDRS motor score. In fact, significant reduction in serum alpha-carotene and lycopene were shown in advanced stage PD patients relative to early stage PD patients. However, no significant differences and no significant correlation were found in serum retinol, alpha- and gamma-tocopherols and other carotenoids in PD patients. 

In response to the study, ExcelVite Nutrionist CheeYen Lau says, “We are delighted to learn that high dietary intake of alpha-carotene, beta-carotene and lycopene are linked with reduced risk or progression of PD. In fact, a previous publication The Association between Mediterranean Diet Adherence and Parkinson’s Disease shows lower adherence to Mediterranean diet (ie: low consumption of fruits and vegetables) is associated with PD status. Alpha-carotene, beta-carotene and lycopene are highly available in bright colored fruits and vegetables, therefore increased consumption of red, orange and yellow colored fruits and vegetables may help to reduce the risk of PD development.”

“Apart from ingesting carotenoid-rich foods, a convenient way of attaining high levels of alpha-carotene and beta-carotene is via dietary supplements. EVTene is a natural mixed-carotenoid complex concentrated from the fruit of oil palm that contains high amounts of both alpha- and beta-carotene as well as a small amount of other carotenoid such as lycopene. As a matter of fact, EVTene contains the highest level of alpha-carotene among all the carotene sources in the market (12 times higher alpha-carotene than Dunaliella salina - algae beta-carotene). Alpha-carotene is only found in trace level in fermentative beta-carotene, B. trispora. Hence, EVTene is an excellent choice of dietary source of important carotenes for brain health and function especially among the elders,” Lau adds.

The study was published in Nutrition Research and Practice and is available online.

Related Articles

Nutrition & Health News

Camelina oil shown to improve blood lipid profile

09 Jan 2018 --- The use of camelina oil reduces overall and LDL cholesterol levels in people with impaired glucose metabolism, according to a new study from the University of Eastern Finland. The study, published in Molecular Nutrition & Food Research, analyzed the associations of camelina oil, fatty fish and lean fish with lipid and glucose metabolism, and low-grade inflammation. 

Nutrition & Health News

Ingestible skincare: Lycored promotes beauty as a holisitic experience

21 Dec 2017 --- Carotenoid-based wellness products supplier Lycored is coming at the skincare market from an interesting angle thanks to its understanding that beauty goes way beyond skin deep. “The vision and the motivation behind becoming ingestible skincare leaders is the understanding that beauty is a holistic experience,” says Golan Raz, Head of the Global Human Health Division at Lycored.

Nutrition & Health News

EVNol Tocotrienol may beat omeprazole in controlling gastric issues

12 Dec 2017 --- ExcelVite’s EVNol tocotrienol was found to be more effective in treating gastric growth factors in stress-exposed rats than omeprazole, a common medication used in the treatment of gastroesophageal reflux disease and peptic ulcer disease. This is according to a recently published study in the World Journal of Gastroenterology that suggests more investigation is warranted.
 

Nutrition & Health News

Lycored to showcase fortified fruit gummies with carotenoid-derived colors

24 Nov 2017 --- Lycored has announced that it is to demonstrate at Food Ingredients Europe this year how its carotenoid-derived colors are perfect for fruit gummies. The global carotenoid supplier will be handing out fortified gummies in six different fruit flavors. Their colors are achieved using Tomat-O-Red (Lycored’s range of reds to pink from tomato-derived Lycopene) and Lyc-O-Beta (yellows and oranges from BetaCarotene).

Nutrition & Health News

Peruvian companies hope Europe goes nuts for its new “superseed” sacha inchi

22 Nov 2017 --- Peru is going to make a big effort to introduce sacha inchi to the European market this autumn. This is according to Andean & Amazonian Super(b) Foods, a news platform set up by the companies CBI, PromPeru, Adex and CCL to promote Peruvian foods. Sacha inchi is a nut-like seed with strong health benefits and the platform states that it “will be one of the stars of the Peruvian participations in Food Matters Live and Fi Europe this autumn.”

More Articles
URL : http://www.nutritioninsight.com:80/news/negative-correlation-found-between-alpha-beta-carotene-and-parkinsons-disease.html