Negative Correlation Found Between Alpha, Beta Carotene and Parkinson's Disease

ea179698-38e5-420c-b63f-93ff932ca69barticleimage.jpg

25 May 2017 --- A new study has shown that serum alpha-carotene, beta-carotene and lycopene may contribute to increased risk and progression of Parkinson’s disease (PD). According to the authors, the study's findings support the notion that carotenes play an important role in the pathogenesis and progression of PD. Serum levels of antioxidants such as alpha-carotene, beta-carotene, retinol, alpha- and gamma-tocopherol, lutein, zeaxanthin and beta-cryptoxanthin were measured and compared between 104 patients with idiopathic PD (Early PD: Hoehn and Yahr stage I and II, N = 47; and Advanced PD: Hoehn and Yahr stage III and IV, N = 57) and 52 healthy controls matched for age and gender. 

The correlation analyses of serum antioxidants and PD progression were performed using Hoehn and Yahr stage and Unified Parkinson’s Disease Rating Scale (UPDRS) motor score to indicate early PD and advanced PD, respectively.

When compared to control, all PD patients showed lower levels of alpha-carotene, beta-carotene and lycopene and negative correlation between Hoehn and Yahr stage and UPDRS motor score. In fact, significant reduction in serum alpha-carotene and lycopene were shown in advanced stage PD patients relative to early stage PD patients. However, no significant differences and no significant correlation were found in serum retinol, alpha- and gamma-tocopherols and other carotenoids in PD patients. 

In response to the study, ExcelVite Nutrionist CheeYen Lau says, “We are delighted to learn that high dietary intake of alpha-carotene, beta-carotene and lycopene are linked with reduced risk or progression of PD. In fact, a previous publication The Association between Mediterranean Diet Adherence and Parkinson’s Disease shows lower adherence to Mediterranean diet (ie: low consumption of fruits and vegetables) is associated with PD status. Alpha-carotene, beta-carotene and lycopene are highly available in bright colored fruits and vegetables, therefore increased consumption of red, orange and yellow colored fruits and vegetables may help to reduce the risk of PD development.”

“Apart from ingesting carotenoid-rich foods, a convenient way of attaining high levels of alpha-carotene and beta-carotene is via dietary supplements. EVTene is a natural mixed-carotenoid complex concentrated from the fruit of oil palm that contains high amounts of both alpha- and beta-carotene as well as a small amount of other carotenoid such as lycopene. As a matter of fact, EVTene contains the highest level of alpha-carotene among all the carotene sources in the market (12 times higher alpha-carotene than Dunaliella salina - algae beta-carotene). Alpha-carotene is only found in trace level in fermentative beta-carotene, B. trispora. Hence, EVTene is an excellent choice of dietary source of important carotenes for brain health and function especially among the elders,” Lau adds.

The study was published in Nutrition Research and Practice and is available online.

To contact our editorial team please email us at editorial@cnsmedia.com

Related Articles

Nutrition & Health News

Weekly Digest: Valensa's Saw Palmetto gains sustainable logo

18 May 2018 --- The past week saw Valensa International gain sustainable recognition with the Fresh from Florida logo for their Saw Palmetto product, as well as USP’s (United States Pharmacopeia) Dietary Supplement Verification Program nabbing the top spot for reliability as determined by pharmacists in a survey conducted by the Pharmacy Times. Furthermore, in clinical news, omega 3 and omega 6 were found to aid the regulation of blood glucose levels in rats. The findings open up the potential for the use of supplements in type 2 diabetes regulation.

Nutrition & Health News

Oral health: Natural products rising and good-for-your teeth sweets

15 May 2018 --- In line with the personal care market, oral health products are increasingly marketing themselves from a natural positioning, as well as a cosmetic one. “Beauty from within” claims all contribute to a more holistic understanding of wellbeing and consumers are increasingly looking to inherent health benefits from natural ingredients which convey better-for-you appeal. NutritionInsight covers a range of innovative products and suppliers tapping into the tooth-care market. When it comes to teeth, more than a shiny, white veneer is the goal: strong teeth and a healthy mouth – chemical free, are increasingly in demand. 

Nutrition & Health News

Weekly Digest: Gencor tackles transparency on the botanical market, carotenoids could enhance sunscreen

11 May 2018 --- This week Lycored adds to research on carotenoids finding that they hold UV protective properties as well as complementing traditional sunscreens, while Gencor, a botanical ingredient supplier, tackles the issue of transparency and adulteration on the botanical market in a bid to strengthen consumer confidence. In the world of mineral salts, Macco group acquire Isaltis to cement a stronger foothold in the market.

Nutrition & Health News

Kamut wheat-based replacement diet could benefit patients with NAFLD, study shows

03 May 2018 --- Kamut Brand khorasan wheat products may help reduce metabolic risk factors and ameliorate the liver profile in patients with non-alcoholic fatty liver disease (NAFLD), according to a study in The Journal of the American College of Nutrition. Secondary prevention improvements, including the reduction in inflammation and cholesterol, were also evident. 

Nutrition & Health News

Fish protein found to prevent “Parkinson's protein” formation, study shows

23 Apr 2018 --- A common protein found in species of fish, parvalbumin, may prevent the formation of specific protein structures that are closely associated with Parkinson’s disease. The study, conducted at the Chalmers University of Technology, Sweden, shines a light on the link between fish consumption and brain health and expands the healthy reputation of fish beyond the famous omega fatty acids.

More Articles
URL : http://www.nutritioninsight.com:80/news/negative-correlation-found-between-alpha-beta-carotene-and-parkinsons-disease.html