Oikos’ new “first-of-its-kind” yogurt boosts muscle retention during GLP-1 weight loss
Tapping into robust demand for nutritional food support tailored for GLP-1 weight loss, Danone’s brand Oikos has introduced a “first and only” yogurt drink in the US designed to support the unique nutrition needs of these consumers — Oikos Fusion. The launch features a patented nutrient blend of whey protein, leucine, and vitamin D, designed to build and retain muscle mass during weight loss.
The brand highlights these three key nutrients have been extensively researched in populations at risk for muscle loss, including two clinical trials conducted by Danone. It claims they “maximally trigger” muscle synthesis with a balanced diet and exercise.
“Pairing Danone’s decades of science expertise with the Oikos brand’s emphasis on strength and high-quality protein enabled us to create something truly unique for people looking to maintain muscle mass while on a weight loss journey,” says Rafael Acevedo, president of Yogurt at Danone North America.
“The growing need for tailored nutrition solutions for people experiencing muscle mass loss is something we can expertly tackle. We know change takes strength, and we believe weight loss isn’t only about taking things away — it’s about adding and strengthening routines with nutrient-dense products that help people better meet their goals.”

Oikos Fusion drinks will launch in Walmart’s refrigerated section starting this August, with additional retailers rolling them out nationwide in October.
High demand for nutrition support
Muscle mass accounts for approximately 20% of weight lost while on a GLP-1 medication, according to research in The American Journal for Clinical Nutrition.
“People on a weight loss journey often eat less, so it’s crucial to focus on the nutrient density of the foods they do eat. When protein needs are not met, the body will start breaking down muscle to get the amino acids it needs. Fiber is also important considering its role in digestive health and because most Americans fall short on fiber intake,” explains Whitney Evans, Ph.D., registered dietitian and director of Nutrition & Scientific Affairs at Danone North America.
“That’s why we created Oikos Fusion — in listening to GLP-1 users and studying the latest research, we packed as much targeted nutrition as possible into a small, delicious, and convenient bottle to help make it easier to meet key nutrition needs.”
In addition to its patented nutrient blend, the new launch provides 23 g of complete protein to support muscles and 5 g of prebiotic fiber to promote digestive health. It contains no added sugar and is free of artificial sweeteners, synthetic colors, or dyes.
The blend also includes vitamins B3 and B12 to help convert food into energy and offers a good source of calcium and vitamins A and D.
Based on direct insights from those on GLP-1 medications, Oikos prioritizes the compact delivery of this weight loss nutrition, leading to the choice to fill a 7 fl oz bottle format.
Danone also created a dedicated nutrition hub for GLP-1 users to deliver “clear, credible guidance” on the nutritional needs of GLP-1 medication users, featuring expert advice and product recommendations from across its yogurt and water portfolio.
Oikos Fusion is the latest addition to Oikos’ range of high-protein offerings, from yogurt cups and protein shots to the new Oikos Protein Shakes, launched in May as shelf-stable options for protein on-the-go.