The latest edition of Quatrefolic® 360° collection is out!
In 2019, the World Health Organization estimated that one third of global deaths were caused by cardiovascular events. In this new issue of Quatrefolic® 360°, you will learn more about the likely correlation between the active folate 5-MTHF supplementation and cardiovascular health.

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59700
France
HEALTH CATEGORIES
At Gnosis by Lesaffre, we harness the power of microorganisms and biotransformation processes like fermentation to cultivate nutritional actives, probiotics, and nutritional and functional yeasts that benefit human health and wellbeing.
We draw on our focused research and development capabilities, rigorous quality and regulatory standards, and extensive clinical validation procedures so that we can effectively collaborate with nutraceutical and pharmaceutical brands to develop game-changing products that help their customers thrive. We relentlessly explore the potential of microbial biotransformation–an untapped, transformative resource–to develop natural, sustainable, and efficacious solutions.
Quatrefolic®: metabolic active form of folate, available for its biological action, ubiquitous in all body cells for benefit health and wellbeing.
ibSium®: (Saccharomyces cerevisiae CNCM I-3856) is an exclusive beneficial live yeast designed to support a complete intestinal comfort.
VitaMK7®: the naturally fermented vitamin K2 in the form of menaquinone-7 (MK7), produced by Gnosis in its own European manufacturing site through a patent granted biofermentation process.
Quatreflora™: a patented and proprietary strain Saccharomyces cerevisiae CNCM I-3856 indicated for vaginal infections caused by fungi and bacteria.
Mythocondro®: the first Non-Animal Chondroitin Sulfate produced by a patented, green, non-animal fermentation-based manufacturing process with a level of use lower than those of animal CS
Adonat®: the S-Adenosylmethionine, the most important methylating agent of human body.
Noochy Crisp™: First extruded nutritional yeast with an excellent nutritional profile full of nutrients, making it a must-have for health meals and snacks. Consumers will discover a new way to consume nutritional yeast thanks to the crunchiness of Noochy Crisp™
MenaQ7®: the only clinically proven vitamin K2 for bone and heart health. With over 20 clinical studies that prove safe and effective health benefits, MenaQ7’s ironclad science portfolio gives you the confidence that your products will deliver promised health benefits and the ability to offer claims that will gain attention on crowded shelves.

NUTRITION & HEALTH NEWS
Synthetic versus natural ingredients: more than meets the eye
19 May 2022 --- As consumers increasingly seek out natural alternatives for their supplementary needs, industry is observing a knowledge gap surrounding synthetically produced vitamins and minerals. Companies are increasingly... Read More
NUTRITION & HEALTH NEWS
Gnosis by Lessafre reveals low vitamin K levels linked to cognitive dysfunction
27 Apr 2022 --- A large-scale, cross-sectional study has linked vitamin K deficiency to lower cognitive well-being and brain health for elderly people. The Gnosis by Lesaffre research is described as a positive development... Read More
NUTRITION & HEALTH NEWS
Zen and on-trend: Vitafoods spotlights CBD, omega 3s and biotics for holistic health
26 Apr 2022 --- As Vitafoods is around the corner, companies are gearing up for launches ranging from immunity to probiotics and sports nutrition, while showcasing developments in cannabidiol (CBD) and the infant nutrition arena.
NUTRITION & HEALTH NEWS
14 Apr 2022 --- Supplementing with vitamin B complex Quatrefolic may lead to higher chances of clinical pregnancy and live birth than supplementing with B9 (folic acid) alone, a Gnosis by Lesaffre study reveals.
FOOD RESEARCH
Investigation backs Gnosis by Lesaffre’s K2 as MK-7 for sports nutrition and aging
29 Mar 2022 --- New research is helping Gnosis by Lesaffre position its MenaQ7 “vitamin K2 as MK-7” for healthy aging and active nutrition. Shown to counter induce oxidative stress in vascular smooth muscle cells, it... Read More

On the acquisition trail with Gnosis by Lesaffre
15 Feb 2022 --- Following the acquisition of Nattopharma, Gnosis by Lesaffre’s managing director Marc Philouze details the company’s approach to further expansion. Innovation is a key priority, which means companies that can offer new ingredients or products are especially appealing as partners.
Microbiota “still a young field of research,” targeting human, animal and plant health
29 Jun 2021 --- Following Lesaffre’s recent microbiota online seminar, Sophie Legrain-Raspaud, research and application director for Gnosis by Lesaffre, shares how the microbiota field reaches beyond human health research to animal, plant and fermentation studies. Her colleague Hassina Ait-Abderrahim, director of in vitro and bacteria platforms, also details Lesaffre’s latest emerging technologies and upcoming research.
Probiotics answer consumer demands for natural immune support
08 Dec 2020 --- Julie Lemahieu is the market manager of wellness and immune health at Gnosis by Lesaffre, the makers of LifeinU BSCU1, a stable probiotic for immune support. She explains that while immunity is not a new demand, 2020 saw particularly strong demand. Other themes include naturality as some consumers look for alternative ways to maintain their health. The company is also set to soon launch a “disruptive” nutritional yeast.
How has the company benefited from the merger one year ago?
22 Jan 2020 --- Marc Philouze, General Manager at Gnosis by Lesaffre, discusses at CPhI Worldwide 2019 the ways in which the company’s synergies have benefited each other since the merger one year ago. He also indicates how the demand for natural products and fermentation is growing. Moreover, the company is well placed to answer this as an innovation partner following the merger.
Synergies between two health ingredient portfolios
14 May 2019 --- Lesaffre, a key global player in the field of yeast and fermentation, announced the full acquisition of Gnosis, an Italian biotechnology company specialized in the development, manufacturing and sale of fermentation-derived ingredients and natural finished products for use in the pharmaceutical, nutraceutical, veterinary and cosmetic industries at the end of 2018. The move came three years after acquiring a majority shareholding of this company. At Vitafoods 2019, the two companies were presented together for the first time, highlighting the portfolio synergies that exist.

The new benefits of Quatrefolic, the innoactive folate
09 Dec 2021 --- Folate, also known as vitamin B9, is well known for being a mandatory supplement during pregnancy. However, the knowledge of its different forms and benefits may still raise some questions. Gnosis by Lesaffre illustrates the main differences between the two forms of vitamin B9, focusing on the characteristics of Quatrefolic, the active form of folate.This is the question that Professor Luca Tiano will try to answer together with Silvia Pisoni, Global Marketing Manager of Gnosis by Lesaffre, and Blandine Clay, Product Manager.During the webinar, they will illustrate the main differences between the two forms of vitamin B9, focusing on the characteristics of Quatrefolic, the active form of folate. The presentation will focus on its actions on polymorphic metabolisms and the many benefits and claims that Quatrefolic provides for all folate needs.
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