Novonesis banner promoting human health biosolutions after Vitafoods Asia, featuring a smiling woman and child
Home
Vitamin A May Benefit...

Vitamin A May Benefit Patients with Emphysema

20 Nov 2006
Add nutritioninsight as a preferred source on Google
Image

Time- and dose-dependent changes in diffusing capacity, CT density mask score, and HRQL were observed in patients treated with ATRA, suggesting the possibility of exposure-related biologic activity.

20/11/06 Retinoids, a derivative of vitamin A, may provide little clinical benefit for patients with emphysema, shows a new study. In the "Feasibility of Retinoids for the Treatment of Emphysema" (FORTE) study, researchers from David Geffen School of Medicine in Los Angeles enrolled 148 subjects with moderate-to-severe chronic obstructive pulmonary disease (COPD) with a primary component of emphysema. Patients received all-trans retinoic acid (ATRA) at either a low or high dose, 13-cis retinoic acid (13-cRA), or placebo for 6 months followed by a 3-month crossover period. At the end of 6 months, no treatment was associated with an overall improvement in pulmonary function, CT density mask score, or health-related quality of life (HRQL). However, time- and dose-dependent changes in diffusing capacity, CT density mask score, and HRQL were observed in patients treated with ATRA, suggesting the possibility of exposure-related biologic activity. This study appears in the November issue of CHEST, the peer-reviewed journal of the American College of Chest Physicians.

All content and features on this website are copyrighted with all rights reserved. The full details can be found in our privacy statement
Add nutritioninsight as a preferred source on Google
Save in your AIChatGPTGoogle AIClaudePerplexityGrok
Subscribe to our newsletters
PlatformsFood Ingredients FirstNutrition InsightPackaging InsightsPersonal Care InsightsThe World of Food Ingredients
About usContact usAdvertisingSitemapArchiveEditorial team
Follow us
© CNS Media B.V 2026. All rights reserved.
Registered Office: Velperweg 18, 6824 BH Arnhem, The Netherlands
Publisher site|Privacy statement
Image