Trial Further Demonstrates Efficacy of Citricoma for Healthy Weight Loss

16/08/07 HP Ingredients, the manufacturer and supplier of Citricoma a clinically formulated proprietary blend of polymethoxylated flavones (PMFs) and Eurycoma longifolia has announced the results of a new human clinical study that substantiates earlier research demonstrating efficacy of Citricoma on promoting favorable anabolic balance and promoting healthy weight loss. The study findings will be presented at the American College of Nutrition conference in Orlando the end of September.

The six-week placebo-controlled study of 50 moderately overweight men and women sought to elucidate the role of Citricoma in a holistic program of nutritional diet, exercise and stress management.

Overall, says Annie Eng, president of HP Ingredients, the results are truly exciting, and portend a widely available tool for people to use to gently, safely and effectively achieve a healthy weight. 

At the end of the six weeks, the researchers noted the following results: 
• Body weight loss was 2.7 kg for the Citricoma group compared to .78 for the placebo group;
• Body fat loss was 2.4 kg for the Citricoma group and 0.55 kg for the placebo group;
• Cortisol/Testosterone ratio was -15% for the Citricoma group and +7% for the placebo group;
• Total cholesterol lowered by 17% and LDL lowered by 15% for the Citricoma group and no change for the placebo  group; and
• Attrition Rate of 10% for Citricoma group compared to between 30 and 60% for other popular weight loss  programs.

“This study is vastly important on several levels,” says Eng. “Virtually any of the popular, low-calorie diet programs works if followed properly with regular exercise.  However, most of these low-calorie restricted diet programs are hard to follow, and have a high drop out rate.  Citricoma has been shown to be effective in helping dieters to stay with the program by promoting better energy levels and improve overall mood. In tandem, Citricoma promotes favorable cortisol/testosterone balance, which leads to healthy body weight/body fat loss.”

Eng adds that Citricoma supplementation used in conjunction with a weight loss dietary regimen  and aerobic- resistance exercise helps maintain a healthy anabolic state, maintain high energy levels, reduce fatigue, and to prevent the body from entering a catabolic state.  “This enhanced feeling of well-being and energy helps participants stay committed to the program and results in favorable changes in body composition, metabolic hormones, mood, and cardiovascular parameters,” she says. 

The PMFs found in Citricoma represent a class of “super flavonoids” extracted from citrus peels that have been shown to inhibit the 11(beta)‐HSD1 enzymes, thereby reducing systemic and local cortisol concentrations (liver and adipose tissue), promoting healthy blood sugar control and healthy weight loss.

Eurypeptides, the active ingredients in Eurycoma longifolia, are long chains of amino acids that enhance weight loss and maintain high energy levels by maintaining normal levels of cortisol and testosterone during weight loss (anabolic state). Additionally, eurycoma is used to help maintain normal (low) cortisol and normal (high) testosterone levels during the stress of weight loss. This hormonal control provides energy to a person in a weight loss phase while simultaneously helping them lose weight.