Tocotrienols Linked With Improved Metabolic Syndrome

21 Sep 2016 --- ExcelVite has revealed a new human clinical study uncovering a link between its patented product, EVNol SupraBio, and reduction of LDL-cholesterol, diastolic blood pressure and inflammatory markers such as Interlukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α) among metabolic syndrome subjects.

The study randomized 70 adults with metabolic syndrome aged 20-60 years old, to receive either EVNol SupraBio, a bio-enhanced full spectrum palm tocotrienol/tocopherol complex or placebo for 16 weeks. 

Researchers examined at baseline, anthropometric tests, body composition, dietary intake, physical activeness and blood pressure at week 8 and week 16. 

Whereas blood cholesterol and inflammatory markers were determined at baseline and week 16, when compared to baseline, subjects supplemented with tocotrienols showed significant reduction of 13.9% and 10.6% for IL-6 and TNF-α inflammatory markers respectively.

Additionally, the diastolic blood pressure, total cholesterol and LDL-cholesterol also showed reduction by 5.4%, 4.6% and 5.3% respectively. 

“Metabolic syndrome is a cluster of risk factors and we are thrilled to know that subjects supplemented with EVNol SupraBio maintained a healthy range of cholesterol and blood pressure,” said CheeYen Lau, Nutritionist of ExcelVite Sdn. Bhd. 

“To date, this is the first study to show that supplementation with tocotrienol attenuates the production of inflammatory markers such as IL-6 and TNF-α in metabolic syndrome subjects. Both IL-6 and TNF-α are strongly associated with obesity-induced inflammatory process, which constitutes the main contributing factor to metabolic syndrome.” 

Lau discussed the benefits of the supplement, adding,“Tocotrienol is scarce in nature. Therefore, it is highly recommended to consume food or beverages fortified with tocotrienol or dietary supplements to attain the biological effective dosage for health maintenance. One drawback about tocotrienol is that, being a fat-soluble compound, tocotrienol has been proven to have erratic and poor absorption in humans. As such, high concentration or dosage of tocotrienol (from a regular oil extract) may not confer the intended health benefits if the tocotrienols are not being absorbed.”

“EVNol SupraBio- a patented bio-enhanced natural full spectrum palm tocotrienol complex was developed to ensure increased oral absorption of each tocotrienol isoforms of up to 300% when compared to regular tocotrienol oil extract,” explained Lau.

“In this regard, EVNol SupraBio achieves therapeutic blood level at a lower dosage of supplementation, and thereby delivering tocotrienols to cells effectively for their health beneficial properties.” Lau added.