Early introduction of infant food may not be linked to childhood obesity

10/03/06 Does breastfeeding or the age at which other foods are introduced to infants affect the risk of obesity in early childhood? Research on this question has produced mixed results, and a new study found that a child's fatness at age five is not related to being breastfed or the age in infancy when other foods are introduced.

In studying the association between infant feeding and fatness during early childhood, researchers from The Children's Hospital of Philadelphia and Cincinnati Children's Hospital were the first to use a technique called dual- energy X-ray absorpiometry (DXA) to measure adiposity, or body fatness. Previous studies have used body mass index (BMI), which is the conventional method of determining fatness based on measuring height and weight.

"DXA measures the amount of fat tissue more directly than BMI," says Hillary Burdette, M.D., nutrition specialist at The Children's Hospital of Philadelphia and lead investigator of the study, which appears in the March issue of the American Journal of Clinical Nutrition.

This distinction is important, say the researchers, because adiposity, rather than weight, is thought to account for obesity-related illnesses, such as type 2 diabetes, high blood pressure and sleep apnea, among others.  "With the rising prevalence of childhood obesity, interest has increased in determining whether breastfeeding or the delayed introduction of complementary foods - or both - can reduce the risk of later obesity.  We found no such effect," says Dr. Burdette.

Dr. Burdette emphasized, however, that the team's findings in no way diminish the importance of breastfeeding for multiple benefits to mothers and children, including protection from infection and establishing a bond between mother and infant. The American Academy of Pediatrics recommends that infants be exclusively breastfed until at least four months of age.

The researchers used DXA to measure the body composition, particularly the fat tissue, of 313 Caucasian and African American five-year-old children. They had previously gathered information on breastfeeding, infant formula use and the timing of the introduction of complementary foods from the children's mothers when the children were three years old. The researchers defined complementary food as anything other than breast milk, formula or water. They asked mothers when their children started drinking juice or eating infant cereal, baby food or table food.

The research team found no significant difference in fat mass between children that were ever breastfed and those never breastfed. Children who were breastfed for a longer duration and those who were breastfed without concurrent formula feeding did not have significantly lower fat mass than did those children who were never breastfed.  Children also did not differ if they were introduced to complementary foods before or after four months of age.

It has been suggested that children that are exclusively or predominantly breastfed for the first four months of life have a different growth pattern than children who are not fed breast milk for the first four months of life. In this study the researchers found no difference in fatness between these two groups of children at 5 years of age.

Dr. Burdette's co-investigators were Robert C. Whitaker, Mathematica Policy Research, Inc.; Waynitra C. Hall, the Division of Gastroenterology, Hepatology and Nutrition at The Children's Hospital of Philadelphia; and Stephen R. Daniels, Division of Cardiology, Cincinnati Children's Hospital Medical Center and Department of Pediatrics, University of Cincinnati College of Medicine.

The Children's Hospital of Philadelphia was founded in 1855 as the nation's first pediatric hospital.  Through its long-standing commitment to providing exceptional patient care, training new generations of pediatric healthcare professionals and pioneering major research initiatives, Children's Hospital has fostered many discoveries that have benefited children worldwide. Its pediatric research program is among the largest in the country, ranking second in National Institutes of Health funding.  In addition, its unique family-centered care and public service programs have brought the 430-bed hospital recognition as a leading advocate for children and adolescents.

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