The US Council for Responsible Nutrition (CRN) has raised its recommended safe upper level (UL) for magnesium supplements to 500 mg daily for healthy adults. The trade association bases this decision on an updated evaluation of magnesium safety, referring to new human clinical data showing higher levels are well tolerated. Previously, the UL was set at 400 mg per day. The revision is part of CRN’s ongoing updates of its reference book, Vitamin and Mineral Safety. The organization has unveiled a new magnesium chapter and will continue releasing updated nutrient safety chapters.