Cosmax NBT harnesses chrysanthemum in Chrytri launch for muscle health

21 Jul 2021 --- Cosmax NBT has created Chrytri, an ingredient that can aid muscular health. Chrytri is made using Chrysanthemum morifolium, used as a traditional herbal medicine in Korea and China.

“In the sports nutrition category, consumers are seeking more convenient delivery formats such as ready-to-drink products, protein shots or bars. Therefore growing demand for these products shows that sports nutrition products have increasingly gained popularity,” Suyoung Choi, functional ingredient development director at Cosmax NBT, tells NutrtionInsight.

The global sports nutrition market is predicted to grow at a CAGR of 15 percent between 2021 to 2025, according to the company. Transparency and clean label demands are also driving the use of natural ingredients.

This is supported further by Innova Market Insights’ top trend for 2021, “Transparency Triumphs,” which reveals that three in five global consumers are interested in learning more about their food source and how it is made.

As backed by in vitro, in vivo and clinical tests conducted by Cosmax NBT, Chrytri helps improve muscle function and muscle generation, while reducing muscle decomposition.

Chrytris potential
Chrytri can reduce muscle decomposition by inhibiting Atrogin-1 and MuRF1. It also increases muscle synthesis through mTOR activation.

“Atrogin-1 and MuRF-1 are key biomarkers for measuring muscle atrophy and increase muscle atrophy through activation of proteolysis,” Choi states.Chrytri holds the potential to aid in muscle regeneration and strength.

“In detail, Atrogin-1 and MuRF-1 are E3 ubiquitin ligases expressed in skeletal muscle that direct the targeting of polyubiquitination of proteins for proteasome degradation. Chrytri inhibits gene expression of Atrogin-1, MuRF-1.”

Cosmax NBT completed three patent registrations in Australia and South Korea. An additional three patents are pending in the US, China and Australia.

Chrytri is available as a primary ingredient in various delivery formats, including tablets, soft/hard capsules, powders, jellies and gummies.

Chrytris’ effects on muscles study 
A study conducted by Cosmax NBT on the effects of chrytri on mice muscle mass found that in C2C12 mouse muscle cells, the mitochondrial cell density increased according to Chrytri treatment.

Additionally, Chrytri treatment promoted muscle cell differentiation and increased muscle cell protein production.

Finally, in the mouse muscle cells, Chrytri treatment inhibited muscle atrophy and therefore preventing muscle loss.

Muscles in the spotlight
Muscles are related to life expectancy as less muscle strength equates to a higher mortality rate. Muscle loss accelerates with age, decreasing by approximately one percent each year at age 70.

In healthy aging, the elderly have concern for their muscle strength, which is a significant determinant of life quality and longevity, comments Choi.

In this space, Innova Market Insights’ data reveals a 32 percent average annual growth between 2017 to 2020 in food and beverage launches targeting the “Aging Well” segment.

Ingredients benefiting muscle growth
Researchers at the Waseda University in Japan previously found that muscle growth is dependent on the time (of the day) of protein consumption.

By Nicole Kerr