29 Apr 2015 --- Genetically modified crops are usually designed to have herbicide tolerance and insect resistance, but there are other applications of such engineered plants, such as the incorporation of genes for specific nutrients. Research published in the International Journal of Biotechnology suggests that the bio-fortification of rice with a gene to produce more folate (vitamin B9) could significantly reduce the risk of birth defects, such as spina bifida and other neural tube defect conditions, caused by deficiency of this nutrient.