21 Mar 2018 --- A new study in PLOS Biology by researchers at Cornell University has shown that inflammation, driven by obesity, can reduce the number of taste buds on the tongues of mice. According to the researchers, the data suggests that gross adiposity stemming from chronic exposure to a high-fat diet is associated with an inflammatory response causing a disruption in the balancing mechanisms of taste bud maintenance and renewal. The reduction of taste buds can cause further overeating.