Muscular Mass Preservation: New Proven Benefits from Curcumin

06 May 2016

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06 May 2016 --- Following the positive results obtained in sports support, new data demonstrates the potentially interesting effect of Indena’s Meriva in muscular mass maintenance.

A recent registry study, published in the European Review for Medical and Pharmacological Sciences, demonstrates that the addition of Indena’s bioavailable curcumin formulation – Meriva – to a regimen of standardized diet and exercise contributes to improve strength and physical performance in healthy elderly subjects, helping maintaining the muscular mass.

Remarkable improvements in all parameters such as: hand grip; weight lifting; time/ distance before feeling tired after cycling, walking and climbing stairs; general fitness; oxidative stress measurement; Karnofsky scale; cardiac function with respect to baseline values, were observed in the supplementation groups (p <0.05 for all comparisons).

At three months, intergroup comparison also revealed a statistical advantage in all parameters for both supplementation groups compared with the standard managementonly group (p < 0.05 for all comparisons).

“At Indena, we have always been inspired by a rigorous scientific approach in our research to guarantee botanical extracts that make the real difference in our customers’ finished products,” commented Cosimo Palumbo, Indena Marketing Director.

“The safety and efficacy profiles of Meriva are supported by 24 clinical trials and these new positive data broaden the existing findings of dietary supplementation with Meriva on healthy inflammatory response after exercise and Delayed Onset of Muscular Soreness.”

Meriva is a patented delivery form of curcumin based on Indena’s proprietary Phytosome technology, for healthy inflammatory response, joint health and eye health.

Pharmacokinetic comparison studies have shown Meriva to improve the overall curcuminoids bioavailability by about 30-fold, and significant absorption benefits; in particular,r demethoxycurcumin (the most potent curcuminoid in numerous bioassays) was found to be 50-fold more bioavailable as compared to a non-formulated curcumin extract.

Indena technology relies on the use of dietary adjuvants (lecithin) and is supported by 24 clinical trials on efficacy and by a robust tolerability and safety profile.

Indena company is dedicated to the identification, development and production of high quality active principles derived from plants, for use in the pharmaceutical, health food and personal care industries. With over 90 years of botanical experience, the company holds more than 120 primary patents, has published more than 700 scientific studies and co-operates with the world’s most prestigious universities and private research institutions.