Moderate drinking may help to prolong life

15 Aug 2017 --- Light-to-moderate drinking can lower the risk of premature mortality caused by cardiovascular disease, while heavy drinking can significantly increase the risk of premature mortality from cancer, according to a study in the Journal of the American College of Cardiology. Less than 14 drinks a week for men and seven for women “clearly outweigh” possible cancer risk, suggests the study.

Consuming large amounts of alcohol has been linked to a wide range of health issues, including cardiovascular disease, but alcohol in moderation has been recommended by doctors. (link = https://www.nutritioninsight.com/news/frequent-alcohol-consumption-may-reduce-diabetes-risk.html) However, despite these recommendations, studies on the risk of mortality among light-to-moderate drinkers have had inconsistent results. (link = https://www.nutritioninsight.com/news/just-one-alcoholic-drink-a-day-increases-breast-cancer-risk-study.html) Researchers in the latest study examined the association between alcohol consumption and risk of mortality from all-causes, cancer and cardiovascular disease in the US.

The researchers looked at data from 333,247 participants obtained through the National Health Interview Surveys in the US from 1997 to 2009. Study participants were asked questions about their alcohol consumption status and patterns of use.

The participants’ consumption patterns were divided into six categories: lifetime abstainers, lifetime infrequent drinkers, former drinkers and current light (less than three drinks per week), moderate (more than three drinks per week to less than 14 drinks per week for men or less than seven drinks per week for women) or heavy drinkers (more than 14 drinks per week for men or seven drinks per week for women).

“Our research shows that light-to-moderate drinking might have some protective effects against cardiovascular disease, while heavy drinking can lead to death,” says Bo Xi, Associate Professor at the Shandong University School of Public Health in China and the study's lead author. But Xi warns against overindulgence: “A delicate balance exists between the beneficial and detrimental effects of alcohol consumption, which should be stressed to consumers and patients.”

Throughout the length of the study, 34,754 participants died from all causes. Of these, 8,947 deaths were cardiovascular disease-specific (6,944 heart disease-related and 2,003 cerebrovascular-related deaths) and 8,427 deaths were cancer-specific.

Researchers found that male heavy drinkers had a 25 percent increased risk of mortality due to all-causes and a 67 percent increase in mortality from cancer. These increases were not significantly noticed in women. There was no association found between heavy drinking and cardiovascular disease mortality. 

Conversely, moderate drinking was associated with a 13 percent and 25 percent decreased risk of all-cause mortality, and 21 percent and 34 percent decreased risk of cardiovascular disease mortality, respectively, in both men and women. Researchers observed similar findings for light drinking in both men and women.

“We have taken rigorous statistical approaches to address issues reported in earlier studies such as abstainer bias, sick quitter phenomenon and limited confounding adjustment in our study,” says one of the study's authors, Sreenivas Veeranki, Assistant Professor in Preventive Medicine and Community Health at University of Texas Medical Branch. “A J-shaped relationship exists between alcohol consumption and mortality, and drinkers should drink with consciousness.”

In an accompanying editorial, Giovanni de Gaetano, Director of the Department of Epidemiology and Prevention at IRCCS Istituto Neurologico Mediterraneo Neuromed, says that while younger adults should not expect considerable benefit from moderate drinking: “for most older persons, the overall benefits of light drinking, especially the reduced cardiovascular disease risk, clearly outweigh possible cancer risk.”