Kyowa Hakko’s citicoline supplementation may slow glaucoma

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18 Aug 2017 --- A 500mg dose of citicoline from Kyowa Hakko Europe (Kyowa) may significantly slow the progression of visual acuity loss due to glaucoma. This is according to a new study by researchers at the Sao Paolo Hospital Eye Clinic at the University of Milan, who followed 41 patients with progressing glaucoma – a disease that damages the optic nerve and can lead to vision problems and blindness – over two years.

“We are always excited to see that additional scientific data has been established to support its further benefits for eye health,” Oksana Ritchie, the company’s European Marketing Manager, tells NutritionInsight. “We will review our marketing strategy going forward based on these additional findings.”

Rate of progression drops dramatically
The Italian study targeted individuals with primary open-angle glaucoma (POAG), which is associated with increased eye pressure and a resulting loss of the vision field.

Participants were given an oral solution that contained 500mg of citicoline from Kyowa. The results as were described as “astounding” by the company, as the mean rate of progression dropped dramatically compared to the two years prior to the study.

The study also found that there was a statistically significant decrease in intraocular pressure. It is not conclusive that citicoline alone is responsible for the results; however, supplementation with citicoline may be beneficial in overall brain and eye health.

“Kyowa, and also our customers in recent years, have continuously published new science to substantiate the efficacy of this ingredient in various applications,” Ritchie comments on the potential for future, larger-scale studies. “Preparations for different studies to be published over the next coming years are already on our roadmap.”

Future possibilities
Citicoline is described by Kyowa as a “vital nutrient” that helps the brain generate electrical impulses, care for healthy brain cells and protect neurons from free radical damage. It is said to support memory and cognitive function while aiding in the synthesis and maintenance of cell membranes.

When it comes to future possible applications, Ritchie says: “Our [research is] proactively working on extending the use of citicoline for a far wider variety of age groups and target applications, sports nutrition being a good example.”

“Together with specialists in eye health and our customers [who believe] in citicoline benefits, we continue assessing the possibilities of future research and studies about citicoline efficacy for neuroprotection,” she adds.

The study, “Citicoline Oral Solution in Glaucoma: Is There a Role in Slowing Disease Progression?” was published online in Ophthalmologica. A link to the abstract can be found here.

To contact our editorial team please email us at editorial@cnsmedia.com

Kyowa Hakko Europe GmbH

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Kyowa Hakko Europe is offering a line of well-researched branded ingredients and an extensive portfolio of ultra-pure amino acids, vitamins, nucleic acids and related compounds for use in pharmaceutical, nutritional and industrial applications.

Kyowa Hakko Europe together with its daughter company Kyowa Hakko Bio Italia represent the European Sales Force of KYOWA HAKKO BIO CO., LTD., a Japanese company with combined strengths in bio-technology and fermentation. With its innovative and patented fermentation process built over the years, which excludes the usage of any animal origin material, KYOWA has become a trusted pioneer in the healthcare field, making substantial contributions to the health and well-being of people around the world.

Our core business areas:

• Pharmaceuticals
• Supplements & Nutrition

Pharmaceuticals

Pharmaceutical companies around the world purchase our high-quality Active Pharmaceutical Ingredients (API’s) and excipients that can be used in a wide variety of pharmaceutical applications including:

• APIs
• Excipients
• Cell culture media components
• Drug intermediates
• Medical foods

Supplement & Nutrition

Kyowa is committed to producing pure products of the highest quality for life-enhancing benefits. Decades of research and refinement have gone into developing our standards and methods of purification. Our bulk product offerings:

• Meet or exceed high purity standards
• Backed by Kyowa Quality and science
• Are produced with no additives, artificial flavors or preservatives
• Include Kosher and Halal ingredients

Kyowa Quality®

Our ingredients bear the Kyowa Quality mark, which means that all KQ products are manufactured to meet highest quality assurance standards, supplying quality and trusted materials for various industries such as pharmaceuticals, foods, and cosmetics.

Our ingredients are backed by the same standard of excellence that has come to be associated with the KYOWA name.



Kyowa Hakko Branded Ingredients

Our branded ingredients are exclusively manufactured by KYOWA HAKKO BIO CO., LTD., and have been designed and clinically tested to deliver targeted, condition-specific consumer health benefits.

A proprietary form of citicoline, Cognizin® is a potent brain nutrient that’s been clinically shown to support mental energy, focus, attention and recall. Tested in human clinical trials and developed using a patented fermentation process, Cognizin® has a Novel Food status in Europe. It is a pure, allergen-free ingredient that is stable and effective. More >> https://cognizin.com/

 

Kyowa’s branded form of glutathione, a master antioxidant, which protects cells against oxidative damage, detoxifies toxic substances and plays a role in the maintenance of immunological functions. Pure, vegetarian, GMP compliant and approved to be used in dietary supplements. Highly effective and clinically tested ingredient. More >> www.setriaglutathione.com

 

A highly effective and clinically tested ingredient for hydration, endurance and recovery. Its unique dipeptide structure helps fast, easy and effective delivery of two amino acids L-Alanine and L-Glutamine in the body. Sustamine® has GRAS and Novel Food status. It is vegetarian, tasteless, odorless and stable in liquids. More >> www.sustamine.com

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