24 Oct 2019 --- High levels of dietary salt may negatively impact cognitive function by causing a deficiency of the compound nitric oxide, which is vital for maintaining vascular health in the brain. This is according to a new mice study published in Nature by Weill Cornell Medicine researchers. They established that the impaired cognitive function is not due to a loss in blood flow to the brain as originally thought, but rather to the formation of tau protein “clumps,” which is linked to several forms of dementia in humans. The researchers suggest that avoiding excessive salt intake may help to stave off the vascular and neurodegenerative pathologies that underlie dementia in the elderly.