A study has found a significant connection between gut microbiota, aging, and bone health, particularly osteoporosis. The discovery opens doors for microbiome-based interventions against the disorder and its treatment.Published in npj Metabolic Health and Disease, the study of 684 Chinese reveals that those with a Bacteroides-dominant microbiome have a steeper decline in bone mineral density (BMD) with age than those with a Prevotella-dominant microbiome.