Cutting down on cadmium could help prevent endometrial cancer

6a249be1-4744-4035-bef1-87c8d38a7239articleimage.jpg

10 Aug 2017 --- A study by researchers at the University of Missouri has found that women with increased levels of cadmium – a metal commonly found in foods such as kidneys, liver and shellfish as well as tobacco – also had an increased risk of endometrial cancer.

More than 31,000 new cases of endometrial cancer are expected to be diagnosed in 2017 and researchers hope the five-year observational study, recently published in PLOS One, could lead to new treatments or interventions to prevent the fourth most common cancer in women.

“Cadmium is an estrogen-mimicking chemical, meaning it imitates estrogen and its effects on the body,” comments lead author Jane McElroy, Ph.D., Associate Professor in the Department of Family and Community Medicine at the MU School of Medicine. “Endometrial cancer has been associated with estrogen exposure. Because cadmium mimics estrogen, it may lead to an increased growth of the endometrium, contributing to an increased risk of endometrial cancer.”

The research team partnered with cancer registries in Missouri, Arkansas and Iowa to identify cases of endometrial cancer. The team enrolled 631 women with a history of endometrial cancer in the study and 879 women without a history of the cancer to serve as a control group.

Participants in the study were asked to complete a survey of more than 200 questions about risk factors potentially associated with endometrial cancer. Once they completed the questionnaire, the women were sent a kit to collect urine and saliva samples. Through tests conducted at the MU Research Reactor, the samples were analyzed for cadmium levels.

“When comparing the cadmium levels of the individuals with endometrial cancer to the control group, we found a statistically significant increased risk of the cancer associated with a woman's cadmium levels,” McElroy said. “We found the rate of endometrial cancer incidence increased by 22 percent in individuals with increased cadmium levels.”

While more research is needed to better understand the risks associated with cadmium, researchers say there are steps individuals can take to limit their cadmium-associated cancer risks.

“We all have cadmium present in our kidneys and livers, but smoking has been shown to more than double a person's cadmium exposure,” McElroy says. “Also, we recommend being attentive to your diet, as certain foods such as shellfish, kidney and liver can contain high levels of cadmium. You don't necessarily need to cut these from your diet, but eat them in moderation. This is especially true if women have a predisposition to endometrial cancer, such as a family history, diabetes or obesity.”

Avoiding cadmium is one of the latest pieces of diet-based advice for avoiding cancer risk. Research has recently found that mice that were fed a tomato-rich diet on a daily basis had a significant reduction in the development of skin cancer tumors, while plant-based diets have been linked to a reduced risk of certain cancers. 

To contact our editorial team please email us at editorial@cnsmedia.com

Related Articles

Health & Nutrition News

“Breakthrough” treatment seeks to protect people with peanut allergies through exposure to peanut protein

20 Nov 2018 --- Medical researchers have developed a new treatment for protection against accidental exposure to peanut. Although the treatment is not a “quick fix,” the researchers note their study results show it is possible for some people with peanut allergy to protect themselves from accidental ingestion by building up their tolerance to peanut over time.

Regulatory News

Oleic acid CHD claims success: US FDA approves qualified claim petition on high level foods 

20 Nov 2018 --- The US Food and Drug Administration (FDA) has responded positively to a petition for a new qualified health claim for edible oils containing oleic acid. As a result, products with an oleic acid content upward of 70 percent, such as certain olive, canola and sunflower oils, can be labeled as carrying cardiovascular benefits, but only when replacing heart-damaging saturated fat.

Health & Nutrition News

Symprove multi-strain supplement linked to re-balancing of gut microbiome

20 Nov 2018 --- “Good” bacteria in the live probiotic Symprove can successfully reach and colonize the gut, where they can modify existing gut flora, according to new research published in the International Journal of Pharmaceutics. Researchers also noted that these bacteria are capable of modifying the immune response in the human body.

Health & Nutrition News

Bitter truth? Coffee drinkers have a higher sensitivity to its bitter taste, study suggests

20 Nov 2018 --- According to a new study from Northwestern Medicine and QIMR Berghofer Medical Research Institute in Australia, the more sensitive you are to the bitter taste in coffee, the more coffee you are likely to drink. 

Health & Nutrition News

Treat: Arla Foods Ingredients launches high-protein indulgent biscuit concept

19 Nov 2018 --- Arla Foods Ingredients has launched a new protein biscuit concept that is touted as being tasty as well providing all the benefits of protein-rich foods. The Whey-Pro Biscuit concept demonstrates that it is possible to combine a high-protein claim with an indulgent taste, says Arla. 

More Articles
URL : http://www.nutritioninsight.com:80/news/cutting-down-on-cadmium-could-help-prevent-endometrial-cancer.html