SunCran Naturelle's bacterial anti-adhesion benefits highlighted in study


23 Jul 2018 --- A recent Rutgers University study has found that Taiyo's SunCran Naturelle, which contains standardized soluble cranberry proanthocyanidins (PACs), limits the ability of pathogenic bacteria to adhere to the urinary tract, thereby supporting urinary tract health while improving gut health.

SunCran Naturelle combines Taiyo’s Sunfiber soluble guar fiber with Fruit d’Or’s Cran Naturelle cranberry juice powder. Taiyo touts the ingredient as a turnkey solution for those looking for prebiotic fiber benefits combined with cranberry juice benefits, without the added sugar. 

Available as a bulk powder, SunCran Naturelle is suitable for functional ready-to-drink beverages as well as for bars, capsules, stick packs and scoopable powders. It is organic, GRAS, Non-GMO Project Certified, gluten-free and low-FODMAP certified

In this recent one-day study, 20 healthy adults (10 men and 10 women) underwent a three-day washout period during which they were restricted from consuming high-flavonoid products. On the morning of the study, they received a 945 mg dose of SunCran Naturelle. Their urine was then collected at regular intervals throughout the day. Their fluid consumption was standardized to avoid dilution of urine samples and allow for detection of anti-adhesion activity if present. Each participants’ urinary pH was confirmed to be above 5.5, to rule out pH as a potential inhibitor of bacterial growth. 

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Image one shows electron micrograph of extra-intestinal pathogenic E-coli. Image two shows the E-coli
agglutinated in the presence of SunCran Naturelle. Property of Taiyo & Fruit d'Or.

The urine samples were then exposed to a suspension of pathogenic E-coli. The results showed: 

  • No anti-adhesion activity was detected in the urine prior to SunCran Naturelle consumption.
  • Overall, 85 percent of participants showed at least a moderate anti-adhesion response after SunCran Naturelle consumption.
  • There were no significant gender differences in the responses. 

“We are pleased with these results that show very robust anti-adhesion effects,” says Taiyo Technical Sales Director Derek Timm, Ph.D., RDN, who also points out that a previous human clinical study showed Sunfiber plus antibiotics was superior to antibiotics alone in modulating pathogenic bacteria in the gut.

“With this research, we are providing holistic solutions targeting both urinary tract and gut health. SunCran Naturelle contains standardized, soluble cranberry PACs, which have been shown to have an anti-adhesion effect against pathogenic bacteria that lead to urinary tract issues. We’ve combined this best-in-class cranberry with a true prebiotic fiber proven to improve gut health and minimize harmful bacteria before they find their way to the urinary tract,” Timm notes.

 “Several significant national and international companies have already taken notice of this product. We’ll be excited to share updates in the coming months.”

“Taiyo and Fruit d’Or have gone to extraordinary efforts to ensure traceability and purity, as well as, to demonstrate the health benefits of our ingredients. By developing SunCran Naturelle, our goal is to provide formulators – and ultimately the public – with safe, trusted and effective product that truly delivers on claims,” Timm concludes.

NutritionInsight has previously interviewed Taiyo's Technical Sales Director, Derek Timm Ph.D, about the company's soluble fiber ingredient: Sunfiber.

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