Study: Mangos May Lower Blood Sugar in Obese Adults

09 Sep 2014 --- Research published in the journal Nutrition and Metabolic Insights found that regular consumption of mango by obese adults may lower blood sugar levels and does not negatively impact body weight. These are important findings considering that approximately 34% of US adults have been classified as obese and given the health concerns related to obesity, such as type 2 diabetes (T2DM) and metabolic syndrome.

"We are excited about these promising findings for mangos, which contain many bioactive compounds, including mangiferin, an antioxidant that may contribute to the beneficial effects of mango on blood glucose. In addition, mangos contain fiber, which can help lower glucose absorption into the blood stream," said Edralin Lucas, PhD, associate professor of nutritional sciences at Oklahoma State University, College of Human Sciences and lead study author.

"Our results indicate that daily consumption of 10 grams of freeze-dried mango, which is equivalent to about one-half of a fresh mango (about 100 grams), may help lower blood sugar in obese individuals."

This pilot study was designed to investigate the effects of mango consumption on anthropometric measurements, biochemical parameters, and body composition in obese adults. Participants completing the 12-week study included 20 adults (11 males and 9 females) ages 20 to 50 years old with a Body Mass Index (BMI) of 30 to 45 kg/m2. The study subjects were asked to maintain their usual diet, exercise habits, and regimen of regularly prescribed medications. 

Each day during the study period, participants consumed 10 grams of freeze-dried mango, and dietary intake was monitored via 3-day food records assessed at baseline and after 6 and 12 weeks of mango supplementation. Anthropometric measurements (height, weight, and circumference of waist and hip) were measured at baseline and after 6- and 12- weeks of mango supplementation. Body composition and blood analyses of fasting blood triglyceride, HDL-cholesterol, glucose, hemoglobin A1c, and plasma insulin concentration were evaluated at baseline and at the end of 12 weeks of mango supplementation. 

The researchers found that after 12 weeks, participants had reduced blood glucose (-4.41 mg/dL, P<0.001), and this glucose lowering effect was seen in both males (-4.5 mg/dL, P=0.018) and females (-3.6 mg/dL, P=0.003). No changes were observed in overall body weight, hip or waist circumference, waist to hip ratio, percent fat mass, and lean mass. However, hip circumference was significantly lower in males (-3.3 cm, P=0.048) but not females.

BMI tended to be higher in females (+0.9 kg/m2, P=0.062) but not males after mango supplementation, although these results were not statistically significant. Overall and by gender, there were no significant changes in triglycerides, HDL-cholesterol, or blood pressure. The blood sugar findings of this study are in agreement with Lucas' previous animal research, which was published in the British Journal of Nutrition. 

"We believe this research suggests that mangos may give obese individuals a dietary option in helping them maintain or lower their blood sugar. However, the precise component and mechanism has yet to be found and further clinical trials are necessary, particularly in those that have problems with sugar control, such as diabetics, are necessary," said Lucas.

Results from this present study could have been influenced by a number of factors including the small sample size, lack of a control group, duration of mango supplementation, inaccurate self-reporting of dietary intake and physical activity level by study subjects, or from lack of compliance with daily mango supplementation as part of the study protocol. Additional human studies with larger sample sizes and of longer duration of mango supplementation should be conducted.

A nutrient rich fruit, mangos contain over 20 different vitamins and minerals, supporting optimal function of processes throughout the body. Mangos are an excellent source of the antioxidant vitamins C and A as well as folate. They are also a good source of fiber, copper, and vitamin B6.