06 Jun 2017 --- The newly closed congress on One Carbon Metabolism and its link with Folate, SAMe and Glutathione - ICHOCM 2017 - has offered new thoughts about the role of folic acid supplementation in pregnancy and its implications in food allergies outcome in children. The increased prevalence of childhood allergic diseases has been well-documented from the 1990s on, but the reasons for this increase are largely unknown. Current evidence points to a multifactorial etiology with a complex genetic predisposition, interacting with key environmental factors, including dietary changes.