Kyowa Hakko’s Citicoline Gets Novel Food Registration Status in Europe
14 Jul 2014 --- Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) delivered a scientific opinion on Citicoline as a novel food ingredient (NFI), concluding on October 2013 that Citicoline is safe under the proposed uses and use levels.
Commission Implementing Decision 2014/423/EU of 1 July 2014 authorising Kyowa Hakko the placing on the market of Citicoline as a novel food ingredient under Regulation (EC) No 258/97 of the European Parliament and of the Council.
Citicoline is intended to be used in food supplements in Europe aimed at adult population at a maximum level of 500 mg/day, and in foods for particular nutritional uses, specifically foods for special medical purposes, at a maximum level of 250 mg/serving, and with a maximum daily intake from these types of foods of 1.000 mg/day.
Citicoline is the generic name for CDP-choline (choline cytidine 5’-pyrophosphate), organic molecule produced endogenously and found in all living cells. Is a source of choline and precursor for the synthesis of phospholipids that are essential constituents of cell membranes, including phosphatidylcholine, phosphatidylserine and phosphatidyl-ethanolamine.
In United States, under Cognizin brand name, Kyowa Hakko USA, Inc. has been marketing Citicoline since the early 1980’s as dietary supplement and created the trademark name in 2004, received self-affirmed Generally Recognized As Safe (GRAS) status in 2009, as food ingredient for use at levels of 250 mg per serving in such products as dietary supplements, beverages, breakfast cereals, chewing gum, pastas, hard candies, milk products, fruit juices and soft candy.
Cognizin Citicoline is often called a “brain nutrient” because it increases levels of several important neurotransmitters including acetylcholine, dopamine and noradrenaline; helps maintain the integrity of neuronal cell membranes and increases energy production in the frontal cortex.
A proprietary form of Citicoline, Cognizin is a potent brain-health nutrient that’s been clinically studied to support mental energy, focus, attention and recall. Tested in human clinical trials and developed using a patented fermentation process, Cognizin is a pure, allergen-free GRAS ingredient that’s stable and effective.
This feature is provided by Nutrition Insight’s sister website, Food Ingredients First.
To contact our editorial team please email us at editorial@cnsmedia.com
Subscribe now to receive the latest news directly into your inbox.
COMPANY DETAILS
Am Wehrhahn 50
Düsseldorf
40211
Germany
www.kyowa.eu
bio-chemicals@kyowa.de
Tel: +49 211 175 450HEALTH CATEGORIES
Kyowa Hakko is an international health ingredients manufacturer and world leader in the development, manufacturing, and marketing of pharmaceuticals, nutraceuticals, and food products. Drawing on its expertise in biotechnology and fermentation, Kyowa produces award-winning branded ingredients such as Cognizin® Citicoline, postbiotics IMMUSE® and EYEMUSE®, Setria® Glutathione and has a strong emphasis on research, science, and innovation.
Our ingredients bear the Kyowa Quality mark, which means that all products are manufactured to meet highest quality assurance standards, supplying quality and trusted materials for various industries such as pharmaceuticals, foods, and cosmetics.
Key branded ingredients include:
IMMUSE®Lactococcus lactis strain Plasma
IMMUSE® is the first lactic acid bacteria that has been clinically researched to directly activate pDCs, a rare subset of immune cells, to provide comprehensive innate and adaptive immune support. It is a well-studied ingredient supported by 30 published studies, 15 human trials and 13 clinical efficacy studies.
Cognizin® Citicoline
Cognizin® Citicoline is a proprietary brain-health nutrient that has been clinically shown to support mental energy, focus, attention and recall. Cognizin® is approved as Novel Food Ingredient in the European Union and can be added to food supplements and food for special medical purposes.
EYEMUSE®Lacticaseibacillus paracasei
EYEMUSE® is a heat-treated probiotic (postbiotic) ofLacticaseibacillus paracasei KW3110 that has shown to combat visual fatigue and promote optimal eye health.
Setria® Glutathione
Known as ‘The Master Antioxidant’, Setria® Glutathione is a tripeptide composed of L-Glutamic acid, L-Cysteine and Glycine. Setria® helps protect cells from the damaging effects of toxins and oxidative stress and plays a key role in supporting immune function.
Setria® Performance Blend
Setria® Performance Blend is a clinically researched blend of glutathione and made in the USA L-Citrulline that may support nitric oxide production. New research in resistance-trained males suggests that Setria® Performance Blend may help sustain NO levels which could lead to reduced fatigue and speed post-workout recovery.
VELOX™ Patented Performance Blend
VELOX™ Blend is a clinically studied blend of two made in the USA amino acids—L-Citrulline and L-Arginine— that has been shown to boost Nitric Oxide levels more rapidly than L-Arginine alone. Help your customers achieve their personal best with VELOX™ Patented Performance Blend .
