IFF Health’s ingredient for men’s bladders gains Non-GMO certification

02 Jul 2020 --- IFF Health’s Go-Less Men plant-based ingredient for healthy bladder function in men has received Non-GMO Project Verified certification. Go-Less Men is based on bioactive components found in pumpkin seeds (Cucurbita pepo L.). The product is supported by clinical trials, the company says, which revealed that pumpkin seed extract can help support improved urinary flow rate and voiding time. Moreover it can reduce residual urine volume in men suffering from benign prostatic hyperplasia (BPH).

“This verification offers the highest transparency about GMOs. Go-Less Men is produced via a proprietary production process that guarantees the highest purity and stability. With the Non-GMO Project Verified certification, we go one step further to offer the highest transparency and trust to our customers,” Moran Werner Saido, Product Manager at IFF Health, tells NutritionInsight.

“Go-Less Men is supported by science, non-allergenic and has been shown to support the maintenance of a healthy bladder and prostate. It also is available in pharmaceutical grade,” adds Moran Werner Saido, Product Manager for IFF Health.

Non-GMO is one of the fastest-growing claims in the US food industry. A key factor driving the growth of the market is the expanding demand for non-GMO products as a result of increasing consumer awareness of the sources for the products they consume. The company was granted the new certification from the Non-GMO Project, a nonprofit organization committed to preserving and building sources of non-GMO products, educating consumers and providing verified non-GMO choices.

The Go-Less Men ingredient is sourced from 100 percent European-grown pumpkin.The Go-Less Men ingredient is sourced from 100 percent European-grown pumpkin. It is manufactured using a proprietary decontamination procedure resulting in an oil-free pumpkin seed extract with ensured increased stability, purity and solubility. The process also eliminates susceptibility to rancidity.

“GoLess Men is manufactured under Good manufacturing practices (GMP) and cGMP conditions using IFF Health’s EFLA HyperPure proprietary technology. This allows for the highly selective removal of unwanted contaminants. Moreover, the EFLA HyperPure technology removes the remaining fat residuals and stops fat degradation. This allows the product to be water-soluble and makes it convenient for a wide range of product applications. Our customers use GoLess Men in a variety of applications like capsules, tablets, powder, liquid and others,” Saido explains. 

Backed by science
In a recent clinical study, Go-Less Men demonstrated a capacity to lower urinary symptom frequency and severity in men with benign prostate hyperplasia (BPH). Specifically, the results showed that 500 mg taken daily for 12 weeks provided statistically significant reductions in symptoms based on the total International Prostate Symptom Score (IPSS), and of all BPH related symptoms, with 30 percent of men reporting improvement of symptoms from “moderate/severe” to “mild.”

“The studies showed a marked overall improvement of symptoms associated with BPH following treatment with Go-Less Men,” Saido adds.

The clinical results, he says, were statistically significant and showed that:

• 78.6 percent reported an overall improvement of BPH-associated symptoms.
• 40 percent reduction in nocturnal micturition among elderly men. 
• Effectively reduce in-bladder pressure and urinary frequency.
• Significant drop in post-void urinary volume from 83.97 ml to 63.11 ml.
• Significant improvement in the quality of life parameters.

Last year, an oil-free hydroethanolic pumpkin seed extract by IFF, EFLA 940, used in the product Go-Less Men, was found to alleviate symptoms associated with BPH in a monocentric study at the Institute of Pharmaceutical Sciences at the University of Graz, Austria. Positive effects of EFLA 940 are said to begin after four weeks of intake. This response was shown to be further augmented over the remaining study period.

By Kristiana Lalou