Gut Microbiota of Athletes is More Diverse Than That of Controls

11 Jun 2014 --- Scientists at the Science Foundation Ireland-funded Alimentary Pharmabiotic Centre (APC) at University College Cork and Teagasc Food Research Centre, Moorepark, have carried out a study in conjunction with the Irish Rugby Football Union that has revealed that exercise and associated dietary changes influence gut microbial diversity. The research is published this week in the leading international journal Gut.

The importance of our gut microbes to health and defence against disease is becoming ever more apparent. In particular, high microbial diversity has been associated with increased health whereas a low diversity of gut microbes has been associated with several diseases and syndromes, including obesity.

To investigate the impact of exercise and diet, scientists at the Alimentary Pharmabiotic Centre studied a group of “elite” athletes – the Irish Rugby football team. The study was carried out with 40 male elite professional rugby players (mean age 29; mean BMI = 29.1) immediately prior to the last Rugby World Cup.  Because of the physical size of modern rugby players, two groups of healthy male controls of similar age but with BMIs of >28 and <25 were used.  

This study highlighted that the gut microbiota of our National Rugby team had a very high diversity relative to the Irish general public (as revealed by High Throughput Sequencing).  

The athletes are an exceptional group in terms of their dietary intake, fitness/endurance and now we know, in relation to their gut microbiota!  This high diversity is particularly linked with exercise and protein consumption and suggests that eating specific proteins and/or exercise can provide a means of increasing microbial diversity in the gut.

This is the first report that exercise increases microbial diversity in humans.  While we and others have previously shown that diet influences microbial diversity, we can now report that protein consumption, in particular, positively correlates with microbial diversity.

The study poses new questions and the Cork team is now prospectively testing the impact of exercise on the microbiota in amateurs of various degrees of fitness and will distinguish the effects of exercise from associated dietary changes. Original Article

Clarke, S.F., Murphy, E.F., O’Sullivan, O., Lucey, A.J., Humphreys M, Hogan, A., Hayes, P., O’Reilly, M, Jeffery, I.B., Wood-Martin, R., Kerins, D.M., Quigley, E., Ross, R.P., O’Toole, P.W., Molloy, M.G., Falvey, E., Shanahan, F & Cotter, P.D. Gut 2014 Published online first 09/06/2014 doi: 10.1136/gutjnl-2013-306541 “Exercise and associated dietary extremes impact on gut microbial diversity”