23 Jan 2023 --- A new clinical study on DSM’s Fruitflow prebiotic candidate has been conducted with clinical trial company Atlantia, exploring the supplements’ benefits on cardiovascular health and the gut microbiota through the gut-heart axis. The study found that after four weeks of supplementing the water-soluble tomato concentrate, it decreased fasting blood and urine trimethylamine N-oxide (TMAO) levels. Higher TMAO levels have been associated with adverse cardiovascular effects, leading scientists to argue prebiotics potential for cardiovascular health.