28 Nov 2017 --- Scientists from the University of Geneva (UNIGE) in Switzerland have unraveled the factors linking obesity and insulin resistance, as well as the key role played by the liver in the onset of the disease. By deciphering how the protein PTPR- γ – which is increased in the context of obesity – inhibits insulin receptors located at the surface of liver cells, the researchers’ findings in Nature Communications open the door to potential new therapeutic strategies.