Vitamin D Supplementation During Pregnancy Helps Protect Babies Against Asthma

3b2f0462-43ab-4eaf-abbe-62ba227aed14articleimage.jpg

30 May 2017 --- Taking vitamin D supplements during pregnancy can positively modify the immune system of the newborn baby, according to a study published in the Journal of Allergy and Clinical Immunology. A boost to the immune system could help protect the child against asthma and respiratory infections, a known risk factor for developing asthma in childhood.

The researchers from King's College London studied how taking a supplement of 4,400 IU vitamin D3 per day during the second and third trimesters of pregnancy, versus the recommended daily intake (RDI) of 400 IU/day, influenced the immune system of the newborn.

Participants were randomized at 10-18 weeks of pregnancy to high or low doses of vitamin D supplements. The team studied umbilical cord blood from 51 pregnant women to test the responsiveness of the newborn's innate immune system, which forms the body's first line of defense to infection, and T lymphocyte responses, which provide longer-lasting protection.

Blood samples from babies born to mothers supplemented with higher vitamin D3 were found to respond to mimics of pathogen stimulation by greater innate cytokine responses and greater IL-17A production in response to T lymphocyte stimulation. Both types of response are predicted to improve the neonatal defense to infection.

The team believes the effect will likely lead to improved respiratory health in childhood because strong immune responses in early life have been linked to decreased development of asthma.

“The majority of all asthma cases are diagnosed in early childhood implying that the origin of the disease stems in fetal and early life,” says lead researcher, Professor Catherine Hawrylowicz from King's College London.

“Studies to date that have investigated links between vitamin D and immunity in the baby have been observational. For the first time, we have shown that higher Vitamin D levels in pregnancy can effectively alter the immune response of the newborn baby, which could help to protect the child from developing asthma. Future studies should look at the long-term impact on the immunity of the infant.”

“Vitamin D is a promising area of research for asthma. However, this study is just the first step of many needed to explore this topic. Although this study shows that vitamin D supplementation in pregnancy may improve immune responses, much more research is needed to prove whether this does, in fact, lead to reduced asthma rates later in life,” says Dr. Samantha Walker, Director of Research and Policy at Asthma UK.

Vitamin D is produced by the body through exposure to the sunshine or obtained from foods such as fatty fish and egg yolk, and helps the body control calcium and phosphate levels. Vitamin D levels have been linked to a range of health issues including cardiovascular disease and cancer. A recent study on vitamin D and male fertility has suggested that vitamin D has an effect on many aspects of fertility in both genders, including influencing production and maturation of sperm cells in men, egg cell and uterine lining maturation in women, and sex hormone production in both sexes.

Related Articles

Nutrition & Health News

Relief from food allergies may come from antibody drug and food desensitization

12 Dec 2017 --- A clinical trial of 48 children with multiple food allergies which tested antibody drug omalizumab alongside food desensitization treatment resulted in more effective allergy relief compared to placebo, according to a study published in The Lancet Gastroenterology & Hepatology journal.

Nutrition & Health News

Mood food: Diet differentially affects mental health in young and mature adults

12 Dec 2017 --- Diet and dietary practices have a differential effect on mental health in young adults versus older adults, according to research from Binghamton University, State University of New York. The researchers involved have found that young adults appear to be dependent on food that increases availability of neurotransmitter precursors and concentrations in the brain (meat), while the mood in mature adults (over 30 years) may be more reliant on food that increases availability of antioxidants (fruits) and abstinence of food that inappropriately activates the sympathetic nervous system (coffee, high glycemic index and skipping breakfast).

Nutrition & Health News

EVNol Tocotrienol may beat omeprazole in controlling gastric issues

12 Dec 2017 --- ExcelVite’s EVNol tocotrienol was found to be more effective in treating gastric growth factors in stress-exposed rats than omeprazole, a common medication used in the treatment of gastroesophageal reflux disease and peptic ulcer disease. This is according to a recently published study in the World Journal of Gastroenterology that suggests more investigation is warranted.
 

Business News

Nutrition 21 launches US media campaign to support Velositol ingredient

11 Dec 2017 --- Nutrition 21, LLC has partnered with NYC-based media relations firm Pitch Publicity and clinical pharmacist James B. LaValle in a national media tour dedicated to educating consumers about the benefits of its proprietary ingredient, Velositol.

Nutrition & Health News

Soy, cruciferous vegetables linked to fewer breast cancer treatment side effects

11 Dec 2017 --- Consuming soy foods and cruciferous vegetables – such as cabbages, kale, collard greens, bok choy, Brussels sprouts and broccoli – may be associated with a reduction in common side effects of breast cancer treatment in breast cancer survivors, according to a team of scientists led by Georgetown Lombardi Comprehensive Cancer Center. Understanding the role of life style factors with regard to the side effects is important because diet can serve as a modifiable target for possibly reducing symptoms among breast cancer survivors.

More Articles
URL : http://www.nutritioninsight.com:80/news/vitamin-d-supplementation-during-pregnancy-helps-protect-babies-against-asthma.html