Study finds tomato-rich diet cuts skin cancer risk in half

97786c36-facc-4c1e-ae12-b7e01334141farticleimage.jpg

14 Jul 2017 --- Research involving mice that were fed a tomato-rich diet on a daily basis showed a reduction in the development of skin cancer tumors, by up to half in some cases.

The new study at Ohio State University shows how nutritional interventions can alter the risk for skin cancers. It has been published online in the journal Scientific Reports.

It found that male mice fed a diet of 10 percent tomato powder daily for 35 weeks, then exposed to ultraviolet light, experienced, on average, a 50 percent decrease in skin cancer tumors compared to mice that did not eat dehydrated tomato.

The theory behind the relationship between tomatoes and cancer is that dietary carotenoids, the pigmenting compounds that give tomatoes their color, may protect skin against UV light damage, says Jessica Cooperstone, co-author of the study and a research scientist in the Department of Food Science and Technology in the College of Food, Agricultural, and Environmental Sciences at Ohio State.

There were no significant differences in tumor numbers for the female mice in the study. Previous research has shown that male mice develop tumors earlier after UV exposure and that their tumors are more numerous, larger and more aggressive.

“This study showed us that we do need to consider sex when exploring different preventive strategies,” says the study's senior author, Tatiana Oberyszyn, a professor of pathology and member of Ohio State's Comprehensive Cancer Center.

“What works in men may not always work equally well in women and vice versa.”   

There has been much work carried out previously directed towards tomato consumption and various health benefits. 

Previous human clinical trials suggest that eating tomato paste over time can dampen sunburns, perhaps thanks to carotenoids from the plants that are deposited in the skin of humans after eating, and may be able to protect against UV light damage, Cooperstone says.

“Lycopene, the primary carotenoid in tomatoes, has been shown to be the most effective antioxidant of these pigments,” Professor Oberyszyn adds.

“However, when comparing lycopene administered from a whole food (tomato) or a synthesized supplement, tomatoes appear more effective in preventing redness after UV exposure, suggesting other compounds in tomatoes may also be at play.”

Male VS Female Results 
In the new study, the Ohio State researchers found that only male mice fed dehydrated red tomatoes had reductions in tumor growth. Those fed diets with tangerine tomatoes, which have been shown to be higher in bioavailable lycopene in previous research, had fewer tumors than the control group, but the difference was not statistically significant.

Cooperstone is currently researching tomato compounds other than lycopene that may impart health benefits.

Non-melanoma skin cancers are the most common of all cancers, with more new cases (5.4 million in 2012) each year than breast, prostate, lung and colon cancers combined, according to the American Cancer Society.

Despite a low mortality rate, these cancers are costly, disfiguring, and their rates are increasing, according to the US Department of Health and Human Services.

“Alternative methods for systemic protection, possibly through nutritional interventions to modulate risk for skin-related diseases, could provide a significant benefit,” Cooperstone says.

“Foods are not drugs, but they can possibly, over the lifetime of consumption, alter the development of certain diseases,” she says.

This was a three-year study that was supported by the National Institutes of Health through the National Cancer Institute. 

Related Articles

Nutrition & Health News

Ultra-processed foods linked to heightened risk of cancer: major BMJ study

15 Feb 2018 --- Although processed foods have long been thought to be significantly less healthy than non-processed foods, an observational study published yesterday in BMJ has added some stark figures to the link between ultra-processed foods and the risk of cancer. The study concluded that a 10 percent increase in the proportion of ultra-processed foods in the diet is associated with increases of 12 percent in the risk of overall cancer and 11 percent in the risk of breast cancer.

Nutrition & Health News

Plant-based foods could slash a country’s healthcare costs by billions of euros, says study

15 Feb 2018 --- Billions of euros could be saved from a country’s annual healthcare bill over the next years if more people followed a plant-based diet. This is according to a new study published in the Journal of Nutrition which looked at the health and economic consequences of two plant-based eating patterns, a diet with a daily portion of soy foods and a Mediterranean-style diet.

Nutrition & Health News

Façade? British Nutrition Foundation questions benefit of skin beauty nutraceuticals

14 Feb 2018 --- Although there is a growing market for orally consumed beauty supplements that promise “youthful,” “firm” and “glowing” skin, the evidence to support some of the ingredients used in these popular, and often costly, products is limited. This is according to a review of published research conducted by the British Nutrition Foundation (BNF). The review concludes that nutraceuticals for skin may not add further benefit to the effects already obtained from a healthy diet. 

Nutrition & Health News

Saturated fat and sugar can cause depression and anxiety: study

14 Feb 2018 --- A diet rich in saturated fat, such as palm oil, and sugar not only leads to obesity, but it also creates inflammation in the nucleus accumbens, a part of the brain that controls mood and the feeling of reward. This inflammation can lead to depressive, anxious and compulsive behavior and disrupt metabolism, according to a study from the University of Montreal Hospital Research Centre (CRCHUM). The discovery illustrates the vicious circle experienced by people with obesity caused by a diet rich in sugar and saturated fat, with their diet leading to negative emotions, which can stimulate the quest for more comfort through food.

Nutrition & Health News

Aronia as a trending superfruit: RTD start-up ax-water's infused waters

07 Feb 2018 --- Native to the Midwest region of North America, but still largely unknown in the US, the aronia berry is the nutrient-packed superfood for which the consumer health industry has been waiting. This is according to ax-water, a US health and wellness beverage company cornering this new market in the US with a range of aronia berry infused waters. NutritionInsight spoke with Blake Johnson, agriculture and biosystems engineer and Co-Founder of ax-water, about the merits of this “superfruit.”

More Articles
URL : http://www.nutritioninsight.com:80/news/study-finds-tomato-rich-diet-cuts-skin-cancer-risk-in-half.html