Omega 3 Could Help Treat Asthma

c783f122-ec6e-428a-b9b1-d2eb255bcbf5articleimage.jpg

10 Feb 2017 --- Scientists from the University of Rochester Medical Center have discovered that omega 3 fatty acids contained in fish oil could be used to treat patients suffering from asthma.

People with asthma have an imbalance between molecules that dampen inflammation and those that increase inflammation. Using steroids as treatment controls the inflammation and relieves symptoms, but does not cure the underlying disease.

Researchers found that, by using cell cultures from local asthma patients, Omega-3 fatty acid products can reduce the production of IgE, the antibodies that cause allergic reactions and asthma symptoms in people with milder cases of asthma.

However, the study also found that in patients with severe asthma who use high doses of oral steroids, the omega-3 fatty acids are less effective because the corticosteroids block the beneficial effects.

The same researchers previously showed that certain fatty acids contained in fish oil regulate the function of immune cells (B cells). This lead them to further investigate the effects on asthma.

Lead author, Richard P. Phipps, Ph.D., and his team, collected blood from 17 patients at UR Medicine's Mary Parkes Asthma Center and isolated their B immune cells in the laboratory to explore the impact of pure omega-3-derived products on IgE and other molecules that fuel the disease.

Co-authors conducted much of the laboratory and clinical work, and compared the results of the 17 patients to donors of healthy blood cells.

Most of the patients who volunteered for the study were taking corticosteroids in either pill form or by inhaler, depending upon severity of their asthma.

The results showed that all responded to the omega-3 fatty acids to some degree, as evidenced by a reduction in the levels of IgE antibodies.

However, unexpectedly, Phipps said, the cells from a small subset of patients who were taking oral steroids were less sensitive to the omega-3 treatment.

Steroids are usually a very effective treatment for asthma. However, although the science is in the early stages, it appears that when corticosteroids are used steadily, in some cases the steroids reduce some of the body's natural ability to fight asthma-related inflammation, Phipps said.

The URMC discovery coincides with a New England Journal of Medicine study in late December 2016, showing that prenatal exposure to fish oil reduced the risk of wheeze and asthma in children.

Phipps noted that the fish oil used as a dietary supplement in the NEJM study was a special high-quality preparation--and that consumers should use caution when buying fish oil because not all fish oil is the same.

“You really need high-quality, standardized material that's been processed and stored correctly before comparing results from one study to another study,” Phipps said.

“Our study used the pure, biologically active products in fish oil, known as 17-HDHA, and we've provided a clear line of evidence for why intake of high-quality fish oil is good.”

To contact our editorial team please email us at editorial@cnsmedia.com

Related Articles

Nutrition & Health News

First time finding: Allergy to red meat may be a factor in heart disease

18 Jun 2018 --- A team of researchers says it has linked sensitivity to an allergen in red meat to the buildup of plaque in the arteries of the heart. While high saturated fat levels in red meat have long been known to contribute to heart disease for people in general, the new finding suggests that a subgroup of the population may be at heightened risk for a different reason – a food allergen. The study, which is supported by the National Heart, Lung, and Blood Institute, part of the National Institutes of Health and appears in Arteriosclerosis, Thrombosis, and Vascular Biology.

Nutrition & Health News

DSM’s Nutrition Improvement focus: Fresh thinking on global nutrition and food fortification

15 Jun 2018 --- “We work with our customers and the larger malnutrition-fighting community to treat and prevent malnutrition,” Anthony Hehir, Director of DSM’s Nutrition Improvement Business Segment, tells NutritionInsight. Using its solid science and technical heritage, DSM is striving to fight global malnutrition through its “business with a purpose” approach. NutritionInsight spoke to Hehir, gaining an insight into what drives the company’s staple food fortification technologies, research and future nutrition endeavors. 

Nutrition & Health News

Weekly Digest: NP Nutra triples its warehouse space, broccoli named US top vegetable

15 Jun 2018 --- This week in nutrition, research studies affirmed the benefit of vitamin K2 for healthy bones, vitamin E tocotrienol may delay paralysis associated with Alzheimers and vegetables took center stage in the US with a survey identifying broccoli as the nations favorite and large investments were made in school plant-based cafeteria options. At a sports nutrition conference, Nitrosamines positive effects on cognitive function were announced, while National Institutes of Health launched a new app aimed at providing safe information on popular herbs. Concerning expansions, NP Nutra expanded its warehouse in California and Azelis opened a new pharmaceutical manufacturing facility in Germany.

Nutrition & Health News

Sugar shock: 99 percent of US toddlers consume over seven teaspoons daily

14 Jun 2018 --- The daily sugar intake of many US toddlers exceeds the maximum amount recommended for adults, a study has found. Findings showed that 99 percent of a representative sample of US toddlers aged 19 to 23 months consumed an average of just over seven teaspoons of added sugar on a given day – more than the amount in a Snicker's bar. Furthermore, 60 percent of children were found to consume added sugar before age one.

Nutrition & Health News

Fresh or frozen? Deep-frozen orange juice packs extra health punch, study finds

12 Jun 2018 --- Deep-freezing orange juice increases the overall bioaccessibility of healthy compounds such as carotenoids, a study has found. Conducted by Researchers at the Laboratory of Food Color and Quality at the University of Seville, the study concluded that although fresh juice has the highest concentration of carotenoids, juice that has undergone deep freezing has an increased number of carotenoids that are eventually absorbed into the blood.

More Articles
URL : http://www.nutritioninsight.com:80/news/Omega-3-Could-Help-Treat-Asthma.html