Gut Microbiome and Diet May Affect Depression

219cb5ec-90f6-45c8-b9fb-ccb2abdd0435articleimage.jpg

17 Feb 2017 --- An international group of researchers have published a study in the paper, Psychotherapy and Psychosomatic, that demonstrates new links between the intestinal flora and several disorders such as depression.

Persistent low-grade immune-inflammatory processes, such as oxidative and nitrosative stress and hypothalamic-pituitary-adrenal axis activation, are integral to the pathophysiology of major depressive disorder.

The microbiome, intestinal compositional changes, and resultant bacterial translocation add a new element to the bidirectional interactions of the gut-brain axis.

New evidence implicates these pathways in the onset of major depressive disorder.

In addition, abnormalities in the gut-brain axis are associated with several chronic non-communicable disorders, which frequently co-occur in individuals with depression, including but not limited to irritable bowel syndrome, chronic fatigue syndrome, obesity, and type 2 diabetes mellitus.

The composition of the gut microbiota is influenced by several genetic and environmental factors (e.g. diet).

Several lines of evidence indicate that gut-microbiota-diet interactions play a significant pathophysiological role in depression and related medical comorbidities.

Gut dysbiosis and the leaky gut may influence several pathways implicated in the biology of major depressive disorder, including but not limited to immune activation, oxidative and nitrosative stress, and neuroplasticity cascades.

However, methodological inconsistencies and limitations limit comparisons across studies.

The authors conclude that intestinal dysbiosis and the leaky gut may constitute a key pathophysiological link between depression and its medical comorbidities.

This emerging literature opens relevant preventative and therapeutic perspectives.

Related Articles

Nutrition & Health News

Chronic Fatigue Syndrome Linked to Imbalanced Microbiome

26 Apr 2017 --- Scientists have discovered abnormal levels of specific gut bacteria related to chronic fatigue syndrome/myalgic encephalomyelitis, or ME/CFS, in patients with and without concurrent irritable bowel syndrome (IBS). The findings come from researchers at the Center for Infection and Immunity (CII) at Columbia University's Mailman School of Public Health.

Nutrition & Health News

SGS Approved to Audit Against the Gluten-Free Certification Organization Standard

26 Apr 2017 --- SGS, the world’s leading inspection, verification, testing and certification company has been approved as the first Certification Body to audit against the Gluten-Free Certification Organization (GFCO) standards covering all regions of the world.

Nutrition & Health News

Glanbia Introduces Lecithin-Free Agglomeration Technology

26 Apr 2017 --- Glanbia Nutritionals has announced a breakthrough patent-pending agglomeration technology called BevEdge for powdered drink mixes and liquid beverages. Entirely lecithin free, this method of agglomeration is based on an all-protein solution and can be applied to whey-based, milk-based, casein-based and plant-based ingredients, including hydrolysates. This flexibility provides both sports and lifestyle brands with significantly more opportunities to create highly marketable beverages. And with no lecithin, it is a perfect clean label solution.

Nutrition & Health News

Low Fat, High Sugar "Diet" Products Contribute to Weight Gain: US Study

26 Apr 2017 --- A new study has underscored the idea that low fat, high sugar "diet" foods play an important role in unwanted weight gain. Researchers from the University of Georgia found that rats fed a diet high in sugar but low in fat increased body fat mass when compared to rats fed a balanced (rodent) diet. Moreover, the rats fed a high-sugar diet were more likely to experience a range of other health problems, such as liver damage and brain inflammation.

Nutrition & Health News

Colitis Relieving Properties Turmeric Extract BCM-95 Underlined by Study

26 Apr 2017 --- A study has found that while standard curcumin does possess anti-inflammatory properties, BCM-95, a high-potency turmeric extract, is significantly more effective than standard curcumin in reducing colitis related disease activity and inflammatory symptoms. BCM-95 is a proprietary formulation of Arjuna Natural Extracts in a joint venture with Dolcas Biotech LLC and is composed of pure curcuminoids and essential oils from turmeric with a specific content of turmerones.

More Articles
URL : http://www.nutritioninsight.com:80/news/Gut-Microbiome-and-Diet-May-Affect-Depression.html?tracking=Nutrition%20and%20Health%20News