Concord grape juice could inhibit formation of breast cancer tumors- study

14 Mar 2006 --- Also reduces the amount of DNA damage to mammary glands.

14/03/06 Drinking Concord grape juice inhibited the formation of breast tumors in laboratory rats while also reducing the amount of DNA damage to mammary glands, according to a study published in a recent issue of Cancer Letters.

"This study looked at the early, or initiation, stage of cancer development and saw that consuming Concord grape juice actually suppressed the growth of tumors as well as reduced damage to the mammary gland's DNA," explained study senior author, Keith Singletary, Ph.D., Professor of Nutrition, Department of Food Science & Human Nutrition, University of Illinois. "In a related previous study, we saw a similar effect in what we call the promotion stage-a later stage in the development of cancer. Taken together, the results are quite interesting and certainly merit additional study."

"These studies indicate that specific constituents or combinations of phytochemicals in Concord grape juice can block the initiation stage of tumor formation," Singletary explained. Cancer develops over an extended period of time in at least two stages -- initiation and promotion. The initiation, or early stage of cancer, may occur when there is damage to a cell's DNA resulting from a variety of factors including the exposure to carcinogens or to oxygen free radical species. The promotion stage occurs when these "initiated" cells are then stimulated to reproduce faster than surrounding normal cells. "With the results of this study combined with the previous one, we see Concord grape juice having a suppressive effect on both stages of cancer development," Singletary said.

With several large-scale population studies demonstrating that increased fruit and vegetable consumption decreases the risk for numerous cancers, researchers have sought to identify specific foods and phytochemicals that may have cancer preventive properties. There is particular interest in plant substances called polyphenols. Polyphenols are thought to help protect against cancer by suppressing oxidative stress, inhibiting DNA damage to human cells, and slowing down the multiplication of cancer cells. These compounds include the anthocyanin pigments, which give fruits and vegetables their blue and purple colors. One food source that is rich in anthocyanins, and related compounds called proanthocyanidins, is Concord grapes.

According to the USDA proanthocyanidin database, published in 2004, purple grape juice from Concord grapes is higher in proanthocyanidins, on a per serving basis, than any other beverage tested, including red wine and cranberry juice cocktail. Additionally, the total antioxidant capacity of Concord grape juice is among the highest of all foods.

The study was underwritten, in part, by Welch Foods Inc.

Welch's is the world's leading marketer of Concord and Niagara grape-based products, including grape juice and jelly. The company produces a variety of other fruit-based products, including 100 percent juices, juice cocktails, and drinks in the following forms: single serve, bottled, refrigerated, and frozen and shelf-stable concentrates. In addition, Welch's produces a number of fruit spread products under both the Welch's and BAMA brand names.

http://biz.yahoo.com/prnews/060313/nym042.html?.v=37

Related Articles

Nutrition & Health News

Food for Thought: UK Teenagers Losing Learning Time Due to Hunger

27 Jun 2017 --- Teenage pupils in high school can lose around 51 minutes’ worth of vital learning time a day because their concentration levels dip due to hunger. This is according to the results of a survey conducted in the UK by Kellogg’s. The survey results show that 82 percent of teachers in Britain have seen teens arriving at school hungry every day. And nearly four in 10 teachers believed one reason children in their class were hungry was due to their parents being unable to afford food for breakfast.

Business News

Key Interview: Algatech Targets Synergistic Effects to Advance Microalgae Industry

27 Jun 2017 --- Interest in microalgae has surged over the past decade, and as a result, a growing number of companies have sought to develop new products and technologies to harness the myriad health benefits these unicellular species provide. And according to Algatechnologies, we have only seen the tip of the iceberg in terms of microalgae’s potential benefits and applications. 

Nutrition & Health News

Heightened Risk in Rice? Toxicity of Thioarsenates for Plants Uncovered

27 Jun 2017 --- Although it is a staple food in many regions of the world, rice sometimes contains levels of arsenic that are hazardous to our health. An interdisciplinary team of researchers at the University of Bayreuth has now discovered that there are arsenic compounds which have a toxic effect on plants and yet had not previously been considered in connection with chemical analyses of rice and the estimated health risks for humans. The research concerns thioarsenates, compounds made up of arsenic and sulphur, which may be present in rice fields more often than previously assumed. 

Nutrition & Health News

Nanoparticles as Food Additives due for Risk Reassessment: Researchers

27 Jun 2017 --- The anticaking agent E551 silicon dioxide, or silica, has been used widely in the food industry over the past 50 years, and was long thought to be quite safe. Now, however, researchers working on the National Research Programme “Opportunities and Risks of Nanomaterials” have discovered that these nanoparticles can affect the immune system of the digestive tract.

Business News

Buhler Awarded Contract to Support Food Fortification Program in Pakistan

26 Jun 2017 --- To support the fortification of staple foods in Pakistan, the UK-based Food Fortification Program has awarded Bühler a multi-million contract to supply more than 1000 micro feeders in 2017 and 2018. The program is funded with US$48 million from the UK’s Department for International Development. By directly supporting local mills and food factories, the program is aiming to have a substantial impact on the well-being of close to 100 million people.

More Articles
URL : http://www.nutritioninsight.com:80/news/Concord-grape-juice-could-inhibit-formation-of-breast-cancer-tumors-study.html