Cognizin Ingredient Shown to Improve Focus, Concentration and Memory

26 Jan 2011 --- A six-week study conducted at McLean Hospital, a Harvard Medical School affiliate located in Belmont, Mass., was designed to measure and visualize the functional effects of Cognizin on various facets of brain function.

1/26/2011 --- Deborah Yurgelun-Todd, Ph.D., Director of the Cognitive Neuroimaging Laboratory at The Brain Institute at The University of Utah, presented new scientific data on Kyowa Hakko's branded brain health ingredient Cognizin at the SupplySide Science Tour held January 24, 2011, in Irvine, Calif. She highlighted results of a six-week study conducted at McLean Hospital, a Harvard Medical School affiliate located in Belmont, Mass., designed to measure and visualize the functional effects of Cognizin on various facets of brain function.

On the first day of testing, 16 healthy subjects aged 40 - 60 years underwent functional Magnetic Resonance Imaging (fMRI) while completing both the Stroop task, which is designed to measure attention and reaction time, and the Morris Water Maze task, which examines spatial memory. Subjects were then given a daily oral dose of either 500 or 2000 mg of Cognizin for six weeks before a second imaging protocol was conducted.

After completion of the second fMRI imaging test, increased activation was seen during completion of the Stroop interference task. This was accompanied by improved accuracy in generating correct responses. 

These results indicated that use of Cognizin resulted in a better, more accurate performance, accompanied by increased brain metabolism. 
Increased activation was seen during completion of the second Water Maze test as well. This was accompanied by increased time spent in the correct quadrant. These results indicated that use of Cognizin resulted in better spatial memory retrieval, in addition to increased brain metabolism. Results were nearly identical for individuals receiving 500 mg and 2000 mg of Cognizin, confirming that statistically significant improvements in attention, focus, memory and recall can be achieved at dosing levels of 500 mg.

"Neuroimaging data demonstrated increased regional brain activation, which was related to increased concentration, greater ability to focus and improved accuracy on cognitive tasks after subjects received Cognizin," noted Dr. Yurgelun-Todd. "Greater performance on a spatial memory task was also observed."

Cognizin Citicoline is a natural, water-soluble brain health ingredient, and is a well-established part of the cognitive health category. Vast research indicates this safe and effective branded compound helps protect neural tissue from free radical damage. It also supports brain performance by enhancing metabolism and healthy activity. Unlike other single-action ingredients for brain health, Cognizin is multi-functional. It has shown to benefit individuals affected by memory loss, mood/behavioral disorders, mild cognitive impairment and certain vision disorders.

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Kyowa Hakko Europe GmbH

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Kyowa Hakko Europe is offering a line of well-researched branded ingredients and an extensive portfolio of ultra-pure amino acids, vitamins, nucleic acids and related compounds for use in pharmaceutical, nutritional and industrial applications.

Kyowa Hakko Europe together with its daughter company Kyowa Hakko Bio Italia represent the European Sales Force of KYOWA HAKKO BIO CO., LTD., a Japanese company with combined strengths in bio-technology and fermentation. With its innovative and patented fermentation process built over the years, which excludes the usage of any animal origin material, KYOWA has become a trusted pioneer in the healthcare field, making substantial contributions to the health and well-being of people around the world.

Our core business areas:

• Pharmaceuticals
• Supplements & Nutrition

Pharmaceuticals

Pharmaceutical companies around the world purchase our high-quality Active Pharmaceutical Ingredients (API’s) and excipients that can be used in a wide variety of pharmaceutical applications including:

• APIs
• Excipients
• Cell culture media components
• Drug intermediates
• Medical foods

Supplement & Nutrition

Kyowa is committed to producing pure products of the highest quality for life-enhancing benefits. Decades of research and refinement have gone into developing our standards and methods of purification. Our bulk product offerings:

• Meet or exceed high purity standards
• Backed by Kyowa Quality and science
• Are produced with no additives, artificial flavors or preservatives
• Include Kosher and Halal ingredients

Kyowa Quality®

Our ingredients bear the Kyowa Quality mark, which means that all KQ products are manufactured to meet highest quality assurance standards, supplying quality and trusted materials for various industries such as pharmaceuticals, foods, and cosmetics.

Our ingredients are backed by the same standard of excellence that has come to be associated with the KYOWA name.



Kyowa Hakko Branded Ingredients

Our branded ingredients are exclusively manufactured by KYOWA HAKKO BIO CO., LTD., and have been designed and clinically tested to deliver targeted, condition-specific consumer health benefits.

A proprietary form of citicoline, Cognizin® is a potent brain nutrient that’s been clinically shown to support mental energy, focus, attention and recall. Tested in human clinical trials and developed using a patented fermentation process, Cognizin® has a Novel Food status in Europe. It is a pure, allergen-free ingredient that is stable and effective. More >> https://cognizin.com/

 

Kyowa’s branded form of glutathione, a master antioxidant, which protects cells against oxidative damage, detoxifies toxic substances and plays a role in the maintenance of immunological functions. Pure, vegetarian, GMP compliant and approved to be used in dietary supplements. Highly effective and clinically tested ingredient. More >> www.setriaglutathione.com

 

A highly effective and clinically tested ingredient for hydration, endurance and recovery. Its unique dipeptide structure helps fast, easy and effective delivery of two amino acids L-Alanine and L-Glutamine in the body. Sustamine® has GRAS and Novel Food status. It is vegetarian, tasteless, odorless and stable in liquids. More >> www.sustamine.com

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