B Vitamins Can Reduce Schizophrenia Symptoms

afd706fd-5b6a-4cf0-90a4-677f691893a7articleimage.jpg

16 Feb 2017 --- A review of worldwide studies has found that add-on treatment with high-dose b-vitamins - including B6, B8 and B12 - can significantly reduce symptoms of schizophrenia more than standard treatments alone.

The research looking into the effect of vitamin and mineral supplements on symptoms of schizophrenia was funded by The Medical Research Council and University of Manchester, and is published in Psychological Medicine, one of the world’s leading Psychology journals.

Lead author Joseph Firth, based at the University’s Division of Psychology and Mental Health, said, “Looking at all of the data from clinical trials of vitamin and mineral supplements for schizophrenia to date, we can see that B vitamins effectively improve outcomes for some patients.

“This could be an important advance, given that new treatments for this condition are so desperately needed.”

Schizophrenia affects around 1% of the population and is among the most disabling and costly long term conditions worldwide.

Currently, treatment is based around the administration of antipsychotic drugs.

Although patients typically experience remission of symptoms such as hallucinations and delusions within the first few months of treatment, long-term outcomes are poor; 80% of patients relapse within five years.

The researchers reviewed all randomized clinical trials reporting effects of vitamin or mineral supplements on psychiatric symptoms in people with schizophrenia.

In what is the first meta-analysis carried out on this topic, they identified 18 clinical trials with a combined total of 832 patients receiving antipsychotic treatment for schizophrenia.

B-vitamin interventions which used higher dosages or combined several vitamins were consistently effective for reducing psychiatric symptoms, whereas those which used lower doses were ineffective.

Also, the available evidence also suggests that B-vitamin supplements may be most beneficial when implemented early on, as b-vitamins were most likely to reduce symptoms when used in studies of patients with shorter illness durations.

Firth added, “High-dose B-vitamins may be useful for reducing residual symptoms in people with schizophrenia, although there were significant differences among the findings of the studies we looked at.”

“There is also some indication that these overall effects may be driven by larger benefits among subgroups of patients who have relevant genetic or dietary nutritional deficiencies.”

Co-author Jerome Sarris, Professor of Integrative Mental Health at Western Sydney University, added: “This builds on existing evidence of other food-derived supplements, such as certain amino-acids, been beneficial for people with schizophrenia.”

“These new findings also fit with our latest research examining how multi-nutrient treatments can reduce depression and other disorders.”

The research team says more studies are now needed to discover how nutrients act on the brain to improve mental health, and to measure effects of nutrient-based treatments on other outcomes such as brain functioning and metabolic health.

Related Articles

Nutrition & Health News

Chronic Fatigue Syndrome Linked to Imbalanced Microbiome

26 Apr 2017 --- Scientists have discovered abnormal levels of specific gut bacteria related to chronic fatigue syndrome/myalgic encephalomyelitis, or ME/CFS, in patients with and without concurrent irritable bowel syndrome (IBS). The findings come from researchers at the Center for Infection and Immunity (CII) at Columbia University's Mailman School of Public Health.

Nutrition & Health News

SGS Approved to Audit Against the Gluten-Free Certification Organization Standard

26 Apr 2017 --- SGS, the world’s leading inspection, verification, testing and certification company has been approved as the first Certification Body to audit against the Gluten-Free Certification Organization (GFCO) standards covering all regions of the world.

Nutrition & Health News

Glanbia Introduces Lecithin-Free Agglomeration Technology

26 Apr 2017 --- Glanbia Nutritionals has announced a breakthrough patent-pending agglomeration technology called BevEdge for powdered drink mixes and liquid beverages. Entirely lecithin free, this method of agglomeration is based on an all-protein solution and can be applied to whey-based, milk-based, casein-based and plant-based ingredients, including hydrolysates. This flexibility provides both sports and lifestyle brands with significantly more opportunities to create highly marketable beverages. And with no lecithin, it is a perfect clean label solution.

Nutrition & Health News

Low Fat, High Sugar "Diet" Products Contribute to Weight Gain: US Study

26 Apr 2017 --- A new study has underscored the idea that low fat, high sugar "diet" foods play an important role in unwanted weight gain. Researchers from the University of Georgia found that rats fed a diet high in sugar but low in fat increased body fat mass when compared to rats fed a balanced (rodent) diet. Moreover, the rats fed a high-sugar diet were more likely to experience a range of other health problems, such as liver damage and brain inflammation.

Nutrition & Health News

Colitis Relieving Properties Turmeric Extract BCM-95 Underlined by Study

26 Apr 2017 --- A study has found that while standard curcumin does possess anti-inflammatory properties, BCM-95, a high-potency turmeric extract, is significantly more effective than standard curcumin in reducing colitis related disease activity and inflammatory symptoms. BCM-95 is a proprietary formulation of Arjuna Natural Extracts in a joint venture with Dolcas Biotech LLC and is composed of pure curcuminoids and essential oils from turmeric with a specific content of turmerones.

More Articles
URL : http://www.nutritioninsight.com:80/news/B-Vitamins-Can-Reduce-Schizophrenia-Symptoms.html?tracking=Nutrition%20and%20Health%20News